Biotech News Alert: GenSpera (OTCQB:GNSZ) Announces
Partnership With Global Supplier
Company to
Partner with Phyton Biotech for Manufacture of the Key Ingredient in
Mipsagargin
SAN ANTONIO - February 9, 2015 (Investorideas.com
Biotech Newswire) GenSpera, Inc. (OTCQB:GNSZ) today announced a strategic partnership with
Phyton Biotech for the manufacture of thapsigargin, which is derived from the
thapsia plant and is the key ingredient in the company's investigational agent
mipsagargin. Phyton Biotech will offer its Plant Cell Fermentation (PCF®)
development expertise to convert the thapsia plant into a preserved,
fermentable cell line with a goal of creating a sustainable source of high
quality thapsigargin.
"This partnership will revolutionize the way
we obtain thapsigargin to develop our drugs, enabling us to boost supply and
reduce the impurities that can arise when it is extracted from naturally grown
plants," said Craig Dionne, Ph.D., chief executive officer at GenSpera.
"By working with Phyton Biotech, we are leveraging state-of-the-art
biotech that has the potential to improve the efficiency of our production
process. It is through these kinds of partnerships that we can not only develop
new drug candidates, but do so in a way that creates increased product
value."
The announcement comes as GenSpera enters a stage
of continued development of mipsagargin in hepatocellular carcinoma (HCC) and
ongoing trials in glioblastoma (brain cancer) and prostate cancer. This week,
GenSpera will present its long-term business growth plans at the BIO CEO &
Investor conference being held in New York City. Last month, GenSpera presented
positive Phase II study results for mipsagargin in treating HCC at the 2015 Gastrointestinal
Cancers Symposium in San Francisco, Calif., demonstrating a proof of concept
for its intellectual property.
"Working with an innovative partner like
GenSpera, who is committed to developing new treatment options and doing so in
a way that maximizes efficiency and quality, is exciting," said Mark
Mitchell, president at Phyton Biotech. "Phyton has a proven track record
for commercial supply of active pharmaceutical ingredients in the field of
oncology using its PCF process. We share GenSpera's vision of harnessing the
power of the thapsia plant and expanding their capacity with the best
biotech."
About Phyton
Phyton Biotech is the pioneer in Plant Cell
Fermentation (PCF®) for the development and manufacture of plant-based active
ingredients and other complex molecules. Phyton Biotech's development services
business is focused on harnessing plant-derived natural actives and products
for use in the pharmaceutical field (APIs) as well as in food ingredients,
cosmetic, and agricultural industries. Utilizing a proprietary PCF® platform
technology, Phyton offers a time, risk, and cost balanced path to commercially
viable production processes, resulting in the addition of sustainability,
reliability, quality and scalability to a supply chain of an API. Phyton's
unique capabilities address the entire development chain, including selection
and sourcing of plant material, cell line development, process development,
down-stream development, chemical processing, scale-up, and commercial
production. Phyton is also the world's largest commercial provider of high
quality Paclitaxel and Docetaxel API via PCF® to a global customer base of
sterile injectable manufacturers. The company has GMP facilities in Ahrensberg,
Germany and Vancouver, Canada.
About GenSpera
GenSpera
Inc. is a San Antonio-based biotech company that unlocks conventional thinking
to conceive, design, and develop cancer therapies. GenSpera's technology
platform combines a powerful, plant-derived cytotoxin (thapsigargin) with a
patented prodrug delivery system that provides for the targeted release of drug
candidates within tumors. GenSpera's lead drug candidate, mipsagargin, was
granted Orphan Drug designation by the US Food and Drug Administration (FDA) in
2013 for evaluation in patients with hepatocellular carcinoma (liver cancer).
For
additional information on GenSpera, visit www.genspera.com and connect on
Twitter @GenSperaNews, LinkedIn, Facebook, YouTube and Google+.
Cautionary Statement
Regarding Forward Looking Information
This
communication may contain forward-looking statements. Investors are cautioned
that statements in this document regarding potential applications of GenSpera's
technologies or the future prospects of the company constitute forward-looking
statements that involve risks and uncertainties, including, without limitation,
risks inherent in the development and commercialization of potential products,
uncertainty of clinical trial results or regulatory approvals or clearances,
need for future capital, dependence upon collaborators and maintenance of our
intellectual property rights and the acceptance of GenSpera's proposed
therapies by the health community. Actual results may differ materially from
the results anticipated in these forward-looking statements. Additional
information on potential factors that could affect our results and other risks
and uncertainties will be detailed from time to time in GenSpera's periodic
reports filed with the Securities and Exchange Commission.
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