Investorideas.com newswire, breaking biotechnology and pharma news

Tuesday, October 29, 2019

#BioPharma Snapshot; New Growth Strategies Continue for the Industry - (TSXV: $ICO.V) (OTCQB: $ICOTF) (NASDAQ: $ALXN) (NASDAQ: $BIIB) (NASDAQ: $ACHN) (NASDAQ: $PRVB)


#BioPharma Snapshot; New Growth Strategies Continue for the Industry - (TSXV: $ICO.V) (OTCQB: $ICOTF) (NASDAQ: $ALXN) (NASDAQ: $BIIB) (NASDAQ: $ACHN) (NASDAQ: $PRVB)

Point Roberts WA, Delta, BC – October 29, 2019 - Investorideas.com, a leading investor news resource covering pharmaceutical and biotech stocks releases a sector snapshot reporting on the growth of the global monoclonal antibody market and how this is affecting industry decisions moving forward.


Why is this a sector to pay attention to? According to recent industry reports,“ The Monoclonal Antibodies market worldwide is projected to grow by US$47.6 Billion, driven by a compounded growth of 6%.. Poised to reach over US$44.3 Billion by the year 2025, Inflammatory Disease will bring in healthy gains adding significant momentum to global growth.”

As this segment of bio/pharma grows in size and scale, we are seeing it become a more prominent focus for many companies in the industry. At present, the global Monoclonal Antibody Based Products market is chiefly driven by a number of outstanding firms and the major market players are beginning to execute different growth strategies including new product launches, strategic partnerships & collaborations, operational & geographical expansions, joint ventures, mergers & acquisitions and sales to grab a superior business position. Key players include Abbott Diagnostics, Inc., Amgen, Inc., AstraZeneca PLC, Bristol-Myers Squibb Company and Eli Lilly and Company.

Is there room for smaller players?

iCo Therapeutics Inc. (TSXV: ICO) (OTCQB: ICOTF) thinks so. The Company, which identifies existing development stage assets for use in underserved ocular and infectious diseases, recently announced several corporate developments related to their monoclonal antibody product, Bertilimumab.

iCo has been monitoring a current US court-mandated auction process, with respect to systemic uses of Bertilimumab, previously sublicensed to Immune Pharmaceuticals. On October 21, 2019, the bankruptcy court in New Jersey approved a sale order relating to the assignment of the sublicense of iCo's assets to Alexion Pharmaceuticals (NASDAQ: ALXN) . With respect to the court approved assignment to Alexion, iCo did not object and their rights as the sub-licensor will continue under the sublicense agreement if Alexion acquires the asset in accordance with terms submitted to the bankruptcy court. Further approval by Israeli courts will be required. The company expects in the coming weeks to comment on outcomes, a potential new partnership and next steps for this asset.

Bertilimumab is a fully human monoclonal antibody with specificity for human eotaxin-1 and inhibits its function.

Favorable results from pre-clinical assessments resulted in three clinical studies of Bertilimumab conducted in the EU (a total of 126 patients – healthy individuals, patients with a history of seasonal allergic rhinitis and individuals with a history of seasonal allergic conjunctivitis) provided evidence of good safety and tolerability of Bertilimumab when administered by the intravenous (IV) or intranasal route as well as topical application to the eye.

More recently, Bertilimumab has been investigated in two Phase 2 trials. The first trial targeted patients with a skin condition called bullous pemphigoid and revealed good safety and efficacy results. A second trial has been carried out in patients with an inflammatory bowel disease called ulcerative colitis. Results from this trial are still pending. A Phase 2 clinical trial for patients with vernal keratoconjunctivitis and/or atopic keratoconjunctivitis (involving cornea and conjunctiva) is in preparation. A number of other indications have also been considered.

Therapy with Bertilimumab could be useful in treatments of a number of diseases where steroids and immune-suppressants or other drugs may need to be prescribed chronically (a number of these diseases appear to be seasonal), often resulting in adverse reactions that may become serious over time.

Separately, iCo has also solicited bids from CROs for assistance with iCo's wholly-owned ocular Bertilimumab asset. Currently the company expects to engage the Food and Drug Administration regarding an additional Phase 2 study in ophthalmology, to be run by the Company and/or prospective partners.

Biogen Inc. (NASDAQ: BIIB) and Eisai, Co., Ltd. recently announced that, after consulting with the US FDA, Biogen plans to pursue regulatory approval for Aducanumab, an investigational treatment for early Alzheimer’s disease (AD). Aducanumab is a monoclonal antibody that is supposed to prevent or slow down neurodegeneration by removing toxic beta-amyloid plaques from the brain in the early stages of this condition.

The Phase 3 EMERGE Study met its primary endpoint showing a significant reduction in clinical decline, and Biogen believes that results from a subset of patients in the Phase 3 ENGAGE Study who received sufficient exposure to high dose Aducanumab support the findings from EMERGE. Patients who received Aducanumab experienced significant benefits on measures of cognition and function such as memory, orientation, and language. Patients also experienced benefits on activities of daily living including conducting personal finances, performing household chores such as cleaning, shopping, and doing laundry, and independently traveling out of the home. If approved, Aducanumab would become the first therapy to reduce the clinical decline of Alzheimer’s disease and would also be the first therapy to demonstrate that removing amyloid beta resulted in better clinical outcomes.

In the news, “Shares of Biogen surged significantly after it announced new data on Aducanumab in patients with early Alzheimer’s disease (AD). The company released results from a new analysis of a larger dataset of the discontinued ENGAGE and EMERGE phase III studies on Aducanumab in patients with early AD. This analysis was conducted in consultation with the FDA. Biogen and Japanese partner Eisai had discontinued ENGAGE and EMERGE studies, following a futility analysis. Nevertheless, the new data showed that Aducanumab reduced clinical decline of Alzheimer’s disease in such patients as measured by the pre-specified primary and secondary endpoints. Based on this data, the company plans to submit a biologics license application seeking approval of the drug to the FDA in early 2020. The company also reported better-than-expected results for the third quarter of 2019, driven by higher sales of key multiple sclerosis drugs and continued global launch of spinal muscular atrophy drug, Spinraza.”

Based on discussions with the FDA, the Company plans to file a Biologics License Application (BLA) in early 2020 and will continue dialogue with regulatory authorities in international markets including Europe and Japan. The BLA submission will include data from the Phase 1/1b studies as well as the complete set of data from the Phase 3 studies.

The Company aims to offer access to Aducanumab to eligible patients previously enrolled in the Phase 3 studies, the long-term extension study for the Phase 1b PRIME study, and the EVOLVE safety study. Biogen will work towards this goal with regulatory authorities and principal investigators with a sense of urgency.

Biogen isn’t the only company to surge on recent developments, as in recent news, “Shares of Achillion Pharmaceuticals Inc. (NASDAQ: ACHN), rocketed 82% in premarket trading Wednesday (October 16th), after the biopharmaceutical company agreed to be acquired by Alexion Pharmaceuticals Inc. in a cash deal valued at $930 million. Under the terms of the deal, Alexion will pay $6.30 for each Achillion share outstanding, which is 73% above Tuesday's closing price of $3.65 and implies a market-capitalization of $880.05 million. The deal also includes potential for an additional payment for Achillion shares in the form of contingent value rights (CVRs) to be paid if certain clinical and regulatory milestones are achieved. The CVRs include $1 a share for U.S. Food and Drug Administration approval of Danicopan and $1 a share for ACH-5228 phase 3 initiation.”

Danicopan, Achillion's lead drug candidate has received breakthrough therapy designation for treatment in combination with a C5 monoclonal antibody for patients with a rare blood disorder, paroxysmal nocturnal hemoglobinuria (PNH).

Provention Bio, Inc. (NASDAQ: PRVB), a clinical stage biopharmaceutical company dedicated to intercepting and preventing immune-mediated diseases, recently announced that the European Medicines Agency (EMA) has granted PRV-031 (Teplizumab) PRIority MEdicines (PRIME) designation for the prevention or delay of clinical type 1 diabetes (T1D) in individuals at-risk of developing the disease.

PRIME designation is awarded by the EMA to promising medicines that demonstrate the potential to address substantial unmet medical need based on clinical data.  The EMA considers PRIME designations a priority and provides them with special support, including enhanced interactions and dialogue, as well as a pathway for accelerated evaluation and review.

"We are very pleased the EMA recognizes the transformative potential of PRV-031 and has granted this groundbreaking therapy PRIME designation", said Ashleigh Palmerm CEO of Provention Bio.  "Following on the heels of Breakthrough Therapy Designation from the FDA in August, EMA PRIME further validates the rationale for PRV-031 to prevent or delay the onset of clinical T1D in at-risk subjects. We are committed to working closely with both regulatory agencies to bring PRV-031, as quickly as possible, to the many thousands of T1D at-risk individuals who currently have no options to prevent or delay this catastrophic disease."

PRV-031's PRIME designation was based on clinical data from the "At-Risk" Study conducted by TrialNet, which demonstrated that a single 14-day course of PRV-031 significantly delayed the onset of T1D, as compared to placebo, by a clinically-relevant median of at least 2 years in children and adults at high risk of developing clinical T1D. 

PRV-031, also known as Teplizumab, is an anti-CD3 monoclonal antibody (mAb), which is being developed for the interception and prevention of type 1 diabetes (T1D).  The candidate has been the subject of multiple clinical studies involving more than 1,000 subjects with more than 800 patients receiving PRV-031 in those studies. In previous studies of newly diagnosed patients, PRV-031 has consistently demonstrated the capability of preserving beta cell function and reducing the need for exogenous insulin usage.

Provention is currently evaluating PRV-031 in patients newly diagnosed with clinical T1D (the Phase 3 PROTECT Study).  Additional information on the clinical trial is available at www.clinicaltrials.gov.

As the Monoclonal Antibodies market worldwide is projected to grow by US$47.6 Billion, driven by a compounded growth of 6% with inflammatory disease displaying the potential to grow at over 6.4%, the shifting dynamics supporting this growth make it critical for businesses in this space to keep abreast of the changing pulse of the market.

About Investorideas.com - News that Inspires Big Investing Ideas Investorideas.com is a recognized news source publishing third party news, research and original financial content. Learn about investing in stocks and sector trends with our news alerts, articles, podcasts and videos, looking at cannabis, crypto, AI and IoT, mining, sports biotech, water, renewable energy and more. Investor Idea’s original branded content includes the following podcasts and columns : Crypto Corner , Play by Play sports and stock news column, Investor Ideas Potcasts Cannabis News and Stocks on the Move podcast and column,  Cleantech and Climate Change , Exploring Mining,  the AI Eye .

Disclaimer/Disclosure: Investorideas.com is a digital publisher of third party sourced news, articles and equity research as well as creates original content, including video, interviews and articles. Original content created by investorideas is protected by copyright laws other than syndication rights. Our site does not make recommendations for purchases or sale of stocks, services or products. Nothing on our sites should be construed as an offer or solicitation to buy or sell products or securities. All investing involves risk and possible losses. This site is currently compensated for news publication and distribution, social media and marketing, content creation and more. Disclosure is posted for each compensated news release, content published /created if required but otherwise the news was not compensated for and was published for the sole interest of our readers and followers. Contact management and IR of each company directly regarding specific questions. Disclosure: this news article featuring ICOTF is a paid for news release on Investorideas.com – third party (two thousand) More disclaimer info: https://www.investorideas.com/About/Disclaimer.asp Learn more about publishing your news release and our other news services on the Investorideas.com newswire https://www.investorideas.com/News-Upload/ and tickertagstocknews.com Global investors must adhere to regulations of each country. Please read Investorideas.com privacy policy: https://www.investorideas.com/About/Private_Policy.asp

Contact Investorideas.com
800-665-0411

Get more Biotech Investor Ideas – news, articles and stock directories 


Monday, October 28, 2019

Growth in Monoclonal Antibodies in #BioPharma Sector-(TSXV: $ICO.V) (OTCQB: $ICOTF) (NASDAQ: $ALXN) (NASDAQ: $BIIB) (NASDAQ: $ACHN) (NASDAQ: $PRVB)


Growth in Monoclonal Antibodies in #BioPharma Sector-(TSXV: $ICO.V) (OTCQB: $ICOTF) (NASDAQ: $ALXN) (NASDAQ: $BIIB) (NASDAQ: $ACHN) (NASDAQ: $PRVB)

Point Roberts WA, Delta, BC – October 28, 2019 - Investorideas.com, a leading investor news resource covering pharmaceutical and biotech stocks releases a sector snapshot reporting on the growth of the global monoclonal antibody market and how this is affecting industry decisions moving forward.


Why is this a sector to pay attention to? According to recent industry reports,“ The Monoclonal Antibodies market worldwide is projected to grow by US$47.6 Billion, driven by a compounded growth of 6%.. Poised to reach over US$44.3 Billion by the year 2025, Inflammatory Disease will bring in healthy gains adding significant momentum to global growth.”

As this segment of bio/pharma grows in size and scale, we are seeing it become a more prominent focus for many companies in the industry. At present, the global Monoclonal Antibody Based Products market is chiefly driven by a number of outstanding firms and the major market players are beginning to execute different growth strategies including new product launches, strategic partnerships & collaborations, operational & geographical expansions, joint ventures, mergers & acquisitions and sales to grab a superior business position. Key players include Abbott Diagnostics, Inc., Amgen, Inc., AstraZeneca PLC, Bristol-Myers Squibb Company and Eli Lilly and Company.

Is there room for smaller players?

iCo Therapeutics Inc. (TSXV: ICO) (OTCQB: ICOTF) thinks so. The Company, which identifies existing development stage assets for use in underserved ocular and infectious diseases, recently announced several corporate developments related to their monoclonal antibody product, Bertilimumab.

iCo has been monitoring a current US court-mandated auction process, with respect to systemic uses of Bertilimumab, previously sublicensed to Immune Pharmaceuticals. On October 21, 2019, the bankruptcy court in New Jersey approved a sale order relating to the assignment of the sublicense of iCo's assets to Alexion Pharmaceuticals (NASDAQ: ALXN) . With respect to the court approved assignment to Alexion, iCo did not object and their rights as the sub-licensor will continue under the sublicense agreement if Alexion acquires the asset in accordance with terms submitted to the bankruptcy court. Further approval by Israeli courts will be required. The company expects in the coming weeks to comment on outcomes, a potential new partnership and next steps for this asset.

Bertilimumab is a fully human monoclonal antibody with specificity for human eotaxin-1 and inhibits its function.

Favorable results from pre-clinical assessments resulted in three clinical studies of Bertilimumab conducted in the EU (a total of 126 patients – healthy individuals, patients with a history of seasonal allergic rhinitis and individuals with a history of seasonal allergic conjunctivitis) provided evidence of good safety and tolerability of Bertilimumab when administered by the intravenous (IV) or intranasal route as well as topical application to the eye.

More recently, Bertilimumab has been investigated in two Phase 2 trials. The first trial targeted patients with a skin condition called bullous pemphigoid and revealed good safety and efficacy results. A second trial has been carried out in patients with an inflammatory bowel disease called ulcerative colitis. Results from this trial are still pending. A Phase 2 clinical trial for patients with vernal keratoconjunctivitis and/or atopic keratoconjunctivitis (involving cornea and conjunctiva) is in preparation. A number of other indications have also been considered.

Therapy with Bertilimumab could be useful in treatments of a number of diseases where steroids and immune-suppressants or other drugs may need to be prescribed chronically (a number of these diseases appear to be seasonal), often resulting in adverse reactions that may become serious over time.

Separately, iCo has also solicited bids from CROs for assistance with iCo's wholly-owned ocular Bertilimumab asset. Currently the company expects to engage the Food and Drug Administration regarding an additional Phase 2 study in ophthalmology, to be run by the Company and/or prospective partners.

Biogen Inc. (NASDAQ: BIIB) and Eisai, Co., Ltd. recently announced that, after consulting with the US FDA, Biogen plans to pursue regulatory approval for Aducanumab, an investigational treatment for early Alzheimer’s disease (AD). Aducanumab is a monoclonal antibody that is supposed to prevent or slow down neurodegeneration by removing toxic beta-amyloid plaques from the brain in the early stages of this condition.

The Phase 3 EMERGE Study met its primary endpoint showing a significant reduction in clinical decline, and Biogen believes that results from a subset of patients in the Phase 3 ENGAGE Study who received sufficient exposure to high dose Aducanumab support the findings from EMERGE. Patients who received Aducanumab experienced significant benefits on measures of cognition and function such as memory, orientation, and language. Patients also experienced benefits on activities of daily living including conducting personal finances, performing household chores such as cleaning, shopping, and doing laundry, and independently traveling out of the home. If approved, Aducanumab would become the first therapy to reduce the clinical decline of Alzheimer’s disease and would also be the first therapy to demonstrate that removing amyloid beta resulted in better clinical outcomes.

In the news, “Shares of Biogen surged significantly after it announced new data on Aducanumab in patients with early Alzheimer’s disease (AD). The company released results from a new analysis of a larger dataset of the discontinued ENGAGE and EMERGE phase III studies on Aducanumab in patients with early AD. This analysis was conducted in consultation with the FDA. Biogen and Japanese partner Eisai had discontinued ENGAGE and EMERGE studies, following a futility analysis. Nevertheless, the new data showed that Aducanumab reduced clinical decline of Alzheimer’s disease in such patients as measured by the pre-specified primary and secondary endpoints. Based on this data, the company plans to submit a biologics license application seeking approval of the drug to the FDA in early 2020. The company also reported better-than-expected results for the third quarter of 2019, driven by higher sales of key multiple sclerosis drugs and continued global launch of spinal muscular atrophy drug, Spinraza.”

Based on discussions with the FDA, the Company plans to file a Biologics License Application (BLA) in early 2020 and will continue dialogue with regulatory authorities in international markets including Europe and Japan. The BLA submission will include data from the Phase 1/1b studies as well as the complete set of data from the Phase 3 studies.

The Company aims to offer access to Aducanumab to eligible patients previously enrolled in the Phase 3 studies, the long-term extension study for the Phase 1b PRIME study, and the EVOLVE safety study. Biogen will work towards this goal with regulatory authorities and principal investigators with a sense of urgency.

Biogen isn’t the only company to surge on recent developments, as in recent news, “Shares of Achillion Pharmaceuticals Inc. (NASDAQ: ACHN), rocketed 82% in premarket trading Wednesday (October 16th), after the biopharmaceutical company agreed to be acquired by Alexion Pharmaceuticals Inc. in a cash deal valued at $930 million. Under the terms of the deal, Alexion will pay $6.30 for each Achillion share outstanding, which is 73% above Tuesday's closing price of $3.65 and implies a market-capitalization of $880.05 million. The deal also includes potential for an additional payment for Achillion shares in the form of contingent value rights (CVRs) to be paid if certain clinical and regulatory milestones are achieved. The CVRs include $1 a share for U.S. Food and Drug Administration approval of Danicopan and $1 a share for ACH-5228 phase 3 initiation.”

Danicopan, Achillion's lead drug candidate has received breakthrough therapy designation for treatment in combination with a C5 monoclonal antibody for patients with a rare blood disorder, paroxysmal nocturnal hemoglobinuria (PNH).

Provention Bio, Inc. (NASDAQ: PRVB), a clinical stage biopharmaceutical company dedicated to intercepting and preventing immune-mediated diseases, recently announced that the European Medicines Agency (EMA) has granted PRV-031 (Teplizumab) PRIority MEdicines (PRIME) designation for the prevention or delay of clinical type 1 diabetes (T1D) in individuals at-risk of developing the disease.

PRIME designation is awarded by the EMA to promising medicines that demonstrate the potential to address substantial unmet medical need based on clinical data.  The EMA considers PRIME designations a priority and provides them with special support, including enhanced interactions and dialogue, as well as a pathway for accelerated evaluation and review.

"We are very pleased the EMA recognizes the transformative potential of PRV-031 and has granted this groundbreaking therapy PRIME designation", said Ashleigh Palmerm CEO of Provention Bio.  "Following on the heels of Breakthrough Therapy Designation from the FDA in August, EMA PRIME further validates the rationale for PRV-031 to prevent or delay the onset of clinical T1D in at-risk subjects. We are committed to working closely with both regulatory agencies to bring PRV-031, as quickly as possible, to the many thousands of T1D at-risk individuals who currently have no options to prevent or delay this catastrophic disease."

PRV-031's PRIME designation was based on clinical data from the "At-Risk" Study conducted by TrialNet, which demonstrated that a single 14-day course of PRV-031 significantly delayed the onset of T1D, as compared to placebo, by a clinically-relevant median of at least 2 years in children and adults at high risk of developing clinical T1D. 

PRV-031, also known as Teplizumab, is an anti-CD3 monoclonal antibody (mAb), which is being developed for the interception and prevention of type 1 diabetes (T1D).  The candidate has been the subject of multiple clinical studies involving more than 1,000 subjects with more than 800 patients receiving PRV-031 in those studies. In previous studies of newly diagnosed patients, PRV-031 has consistently demonstrated the capability of preserving beta cell function and reducing the need for exogenous insulin usage.

Provention is currently evaluating PRV-031 in patients newly diagnosed with clinical T1D (the Phase 3 PROTECT Study).  Additional information on the clinical trial is available at www.clinicaltrials.gov.

As the Monoclonal Antibodies market worldwide is projected to grow by US$47.6 Billion, driven by a compounded growth of 6% with inflammatory disease displaying the potential to grow at over 6.4%, the shifting dynamics supporting this growth make it critical for businesses in this space to keep abreast of the changing pulse of the market.

About Investorideas.com - News that Inspires Big Investing Ideas Investorideas.com is a recognized news source publishing third party news, research and original financial content. Learn about investing in stocks and sector trends with our news alerts, articles, podcasts and videos, looking at cannabis, crypto, AI and IoT, mining, sports biotech, water, renewable energy and more. Investor Idea’s original branded content includes the following podcasts and columns : Crypto Corner , Play by Play sports and stock news column, Investor Ideas Potcasts Cannabis News and Stocks on the Move podcast and column,  Cleantech and Climate Change , Exploring Mining,  the AI Eye .

Disclaimer/Disclosure: Investorideas.com is a digital publisher of third party sourced news, articles and equity research as well as creates original content, including video, interviews and articles. Original content created by investorideas is protected by copyright laws other than syndication rights. Our site does not make recommendations for purchases or sale of stocks, services or products. Nothing on our sites should be construed as an offer or solicitation to buy or sell products or securities. All investing involves risk and possible losses. This site is currently compensated for news publication and distribution, social media and marketing, content creation and more. Disclosure is posted for each compensated news release, content published /created if required but otherwise the news was not compensated for and was published for the sole interest of our readers and followers. Contact management and IR of each company directly regarding specific questions. Disclosure: this news article featuring ICOTF is a paid for news release on Investorideas.com – third party (two thousand) More disclaimer info: https://www.investorideas.com/About/Disclaimer.asp Learn more about publishing your news release and our other news services on the Investorideas.com newswire https://www.investorideas.com/News-Upload/ and tickertagstocknews.com Global investors must adhere to regulations of each country. Please read Investorideas.com privacy policy: https://www.investorideas.com/About/Private_Policy.asp

Contact Investorideas.com
800-665-0411




 Get more Biotech Investor Ideas – news, articles and stock directories 

Friday, October 18, 2019

Investor Ideas adds New #Stocks in Cannabis (CSE: $IPOT.C), Biotech (Nasdaq: $HEPA), eSport (Nasdaq: $AESE), Defense (CSE: $PRT.C) (OTCQB: $PLRTF) and Mining (CSE: $FLO.C)

Investor Ideas adds New #Stocks in Cannabis (CSE: $IPOT.C), Biotech (Nasdaq: $HEPA), eSport (Nasdaq: $AESE), Defense (CSE: $PRT.C) (OTCQB: $PLRTF) and Mining (CSE: $FLO.C)




Point Roberts WA, Delta BC, October 18, 2019 – (Investorideas.com Newswire) Investorideas.com, a global news source and leading investor resource announces its weekly roundup of stocks added to its global stock directories in cannabis, biotech, eSport, defense and mining.


The newest cannabis, defense and mining companies are all listed on the Canadian Stock Exchange (CSE) with defense company, Plymouth Rock Technologies Inc. dual-listed on the US OTC Board (OTCQB: PLRTF).

The latest biotech and eSport companies are both Nasdaq listed on the Capital Markets board.

New Cannabis Companies:
Isracann Biosciences Inc. (CSE:IPOT) is an Israeli-based company focused on becoming a premier cannabis producer offering low-cost production targeting undersupplied major European marketplaces. Based in Israel's agricultural sector, Isracann will leverage its development within the most experienced country in the world with respect to cannabis research.

New Biotech Companies:
Hepion Pharmaceuticals (NASDAQCM: HEPA) is a clinical stage biopharmaceutical company focused on the development of targeted therapies for liver disease arising from non-alcoholic steatohepatitis (NASH) and chronic hepatitis virus infection (HBV, HCV, HDV). The Company's lead drug candidate, CRV431, reduces liver fibrosis and hepatocellular carcinoma tumor burden in experimental models of NASH. Preclinical studies also have demonstrated antiviral activities towards HBV, HCV, and HDV through several mechanisms. These diverse therapeutic activities result from CRV431's potent inhibition of cyclophilins, which are involved in many disease processes. Currently in clinical phase development, CRV431 shows potential to play an important role in the overall treatment of liver disease - from triggering events through to end-stage disease.

New eSport Companies:
Allied Esports Entertainment (NASDAQCM: AESE) is a leading esports entertainment company with a global network of dedicated esports properties and content production facilities. Its mission is to connect players, streamers and fans via integrated arenas and mobile esports trucks around the world that serve as both competition battlegrounds and everyday content generation hubs. Allied Esports is a subsidiary of Allied Esports Entertainment.

New Defense Companies:
Plymouth Rock Technologies Inc. (CSE: PRT) (OTCQB: PLRTFis developing the next generation of threat detection solutions, with state-of-the-art technological advancements. Our advanced threat detection methods fuse artificial intelligence with augmented reality interfaces to eliminate human operating error. Plymouth Rock products, both airborne and land-based, will scan for threat items at greater "stand-off" distances than current existing technologies. Our unique radar imaging and signal processing technology creates new opportunities for remotely operated, none intrusive screening of crowds in real time.Plymouth Rock's core technologies include: (1) A Millimeter Remote Imaging from Airborne Drone ("MIRIAD"); (2) A compact microwave radar system for scanning shoe's ("Shoe-Scanner"); and (3) Wi-Fi radar techniques for threat detection screening in Wi-Fi enabled zones in buildings and places, such as airports, shopping malls, schools and sports venues ("Wi-Ti").

New Mining Companies:
Fiorentina Minerals Inc. (CSE:FLO) is engaged in the business of mineral exploration and the acquisition of mineral property assets in Canada.  Its objective is to locate and develop economic precious and base metal properties of merit and to conduct its exploration program on the Consortium Project.  The Consortium Project is comprised of three mineral claims covering an area of 1161.10 hectares, located on Vancouver Island, British Columbia, approximately 35 kilometres south of the town of Sayward in the Nanaimo Mining Division.

The directories are not meant as recommendations but as a research tool to discover opportunities and trading ideas in a particular sector.

About Investorideas.com - News that Inspires Big Investing Ideas Investorideas.com is a recognized news source publishing third party news, research and original financial content. Learn about investing in stocks and sector trends with our news alerts, articles, podcasts and videos, looking at cannabis, crypto, AI and IoT, mining, sports biotech, water, renewable energy and more. Investor Idea’s original branded content includes the following podcasts and columns : Crypto Corner , Play by Play sports and stock news column, Investor Ideas Potcasts Cannabis News and Stocks on the Move podcast and column,  Cleantech and Climate Change , Exploring Mining  the AI Eye .

Disclaimer/Disclosure: Investorideas.com is a digital publisher of third party sourced news, articles and equity research as well as creates original content, including video, interviews and articles. Original content created by investorideas is protected by copyright laws other than syndication rights. Our site does not make recommendations for purchases or sale of stocks, services or products. Nothing on our sites should be construed as an offer or solicitation to buy or sell products or securities. All investing involves risk and possible losses. This site is currently compensated for news publication and distribution, social media and marketing, content creation and more. Disclosure is posted for each compensated news release, content published /created if required but otherwise the news was not compensated for and was published for the sole interest of our readers and followers. Contact management and IR of each company directly regarding specific questions.
More disclaimer info: https://www.investorideas.com/About/Disclaimer.asp Learn more about publishing your news release and our other news services on the Investorideas.com newswire https://www.investorideas.com/News-Upload/ and tickertagstocknews.com
Global investors must adhere to regulations of each country. Please read Investorideas.com privacy policy: https://www.investorideas.com/About/Private_Policy.asp

Learn more about our news, PR and social media services at Investorideas.com

Follow us on Twitter https://twitter.com/Investorideas
Download our Mobile App for iPhone and Android  

To sponsor a daily podcast for the month or to be an expert guest please contact us!

Contact Investorideas.com
800-665-0411























Friday, October 4, 2019

Investor Ideas adds New #Stocks in Biotech, (Nasdaq: $IGMS, $SWTX, $STSA) Tech (NYSE: $NET) and Mining (TSXV: $ARU.V, $PER.V)

Investor Ideas adds New #Stocks in Biotech, (Nasdaq: $IGMS, $SWTX, $STSA) Tech (NYSE: $NET) and Mining (TSXV: $ARU.V, $PER.V)

New #Mining Stocks #Podcast Launched – Exploring Mining




Point Roberts WA, Delta BC, October 4, 2019 – (Investorideas.com Newswire) Investorideas.com, a global news source and leading investor resource announces its weekly roundup of stocks added to its global stock directories in biotech, tech and mining.


Added biotech companies include recent Nasdaq IPO’s involved in antibody technologies and biopharmaceuticals, with the life science companies involved in dental care and life sciences technologies, respectively.

The latest tech company, CLOUDFLARE, INC. (NYSE: NET) is a September IPO, cloud technology company.

Mining companies added are TSX Venture listed with operations in Ecuador and Peru. Investor Ideas also is excited to launch its new mining podcast, Exploring Mining, featuring  stock news from TSX, TSXV ,CSE, ASX, NASDAQ, NYSE companies plus interviews with CEO's and leading experts . To be one of our first guests as a CEO of a public company, analyst or expert, call 800 665 0411.   

New Biotech Companies:
IGM BIOSCIENCES, INC. (NasdaqGS: IGMSis a biotechnology company focused on creating and developing engineered IgM antibodies for the treatment of cancer patients. Since 2010, IGM Biosciences has worked to overcome the manufacturing and protein engineering hurdles that have limited the therapeutic use of IgM antibodies. Through its efforts, IGM Biosciences has created a proprietary IgM technology platform for the development of IgM antibodies for those clinical indications where their inherent properties may provide advantages as compared to IgG antibodies.

SPRINGWORKS THERAPEUTICS, INC. (NasdaqGS:SWTX) is a clinical-stage biopharmaceutical company applying a precision medicine approach to acquiring, developing and commercializing life-changing medicines for underserved patient populations suffering from devastating rare diseases and cancer. SpringWorks has a differentiated portfolio of small molecule targeted oncology product candidates and is advancing two potentially registrational clinical trials in rare tumor types, as well as several other programs addressing highly prevalent, genetically defined cancers. SpringWorks’ strategic approach and operational excellence in clinical development have enabled it to rapidly advance its two lead product candidates into late-stage clinical trials while simultaneously entering into multiple shared-value partnerships with industry leaders to expand its portfolio

SATSUMA PHARMACEUTICALS, INC. (NasdaqGS:STSA) is a clinical-stage biopharmaceutical company focused on developing STS101 (dihydroergotamine mesylate (DHE) nasal powder) as an important and differentiated therapeutic option for the acute treatment of migraine.

ENVISTA HOLDINGS CORP (NYSE:NVST) is a global dental products company that develops and provides a comprehensive portfolio of dental consumables, equipment and services to dental professionals covering an estimated 90% of dentists' clinical needs for diagnosing, treating and preventing dental conditions as well as improving the aesthetics of the human smile. Envista's operating companies, Nobel Biocare Systems, Ormco and KaVo Kerr, serve more than one million dentists in over 150 countries.

SMILEDIRECTCLUB, INC. (NasdaqGS:SDC) is the industry pioneer as the first direct-to-consumer medtech platform for transforming smiles. Through our cutting-edge teledentistry technology and vertically integrated model, we are revolutionizing the oral care industry. SmileDirectClub was founded by Alex Fenkell and Jordan Katzman in partnership with Camelot Venture Group. Available in the U.S., Canada, Australia, and the UK, SmileDirectClub is headquartered in Nashville, Tennessee.

10X GENOMICS, INC(NasdaqGS:TXG) is a life science technology company building products to interrogate, understand and master biology to advance human health. The company’s integrated solutions include instruments, consumables and software for analyzing biological systems at a resolution and scale that matches the complexity of biology. 10x Genomics products have been adopted by researchers around the world including 93 of the top global research institutions and 13 of the top 15 global pharmaceutical companies, and have been cited in over 500 research papers on discoveries ranging from oncology to immunology and auto-immune diseases.

NewTech Companies:
CLOUDFLARE, INC. (NYSE: NET)  is on a mission to help build a better Internet. Today the company runs one of the world’s largest networks, with nearly 10 percent of the Fortune 1,000 companies and approximately 18 percent of the top 10,000 websites using at least one Cloudflare product. Cloudflare’s platform protects and accelerates any Internet application online without adding hardware, installing software, or changing a line of code. Internet properties powered by Cloudflare have all web traffic routed through its intelligent global network, which gets smarter with every request. As a result, they see significant improvement in performance and a decrease in spam and other attacks. Cloudflare was named to Entrepreneur Magazine’s Top Company Cultures 2018 list and ranked among the World's Most Innovative Companies by Fast Company in 2019. Headquartered in San Francisco, CA, Cloudflare has offices in Austin, TX, Champaign, IL, New York, NY, San Jose, CA, Washington, D.C., Lisbon, London, Munich, Beijing, Singapore, and Sydney.

New Mining Companies:
Aurania Resources Ltd. (TSXV: ARU.V) (OTCQB: AUIAF) (FSE: 20Q) is a junior mineral exploration company engaged in the identification, evaluation, acquisition and exploration of mineral property interests, with a focus on precious metals and copper. Its flagship asset, The Lost Cities - Cutucu Project, is located in the Jurassic Metallogenic Belt in the eastern foothills of the Andes mountain range of southeastern Ecuador.

Peruvian Metals Corp. (TSXV: PER.V) is a Canadian Exploration and Mineral Processing company. Our business model is to provide toll milling services for clients and to produce high grade concentrates from mineral purchases. The Company continues to acquire and develop precious and base metal properties in Peru.

The directories are not meant as recommendations but as a research tool to discover opportunities and trading ideas in a particular sector.

About Investorideas.com - News that Inspires Big Investing Ideas
Investorideas.com is a recognized news source publishing third party news and press releases plus we create original financial content. Learn about investing in stocks and  sector trends  from Investorideas.com with our news alerts , articles , podcasts and videos  talking about cannabis,  crypto,  technology including  AI and IoT , mining ,sports biotech, water, renewable energy and more . Investorideas.com original branded content includes the daily Crypto Corner and Podcast, Play by Play sports and stock news column, Investor Ideas #Potcasts #Cannabis News and Stocks on the Move podcast and column,  Cleantech and Climate Change Podcast and  the AI Eye Podcast and column covering developments in AI. 

Disclaimer/Disclosure: Investorideas.com is a digital publisher of third party sourced news, articles and equity research as well as creates original content, including video, interviews and articles. Original content created by investorideas is protected by copyright laws other than syndication rights. Our site does not make recommendations for purchases or sale of stocks, services or products. Nothing on our sites should be construed as an offer or solicitation to buy or sell products or securities. All investing involves risk and possible losses. This site is currently compensated for news publication and distribution, social media and marketing, content creation and more. Disclosure is posted for each compensated news release, content published /created if required but otherwise the news was not compensated for and was published for the sole interest of our readers and followers. Contact management and IR of each company directly regarding specific questions.
More disclaimer info: https://www.investorideas.com/About/Disclaimer.asp Learn more about publishing your news release and our other news services on the Investorideas.com newswire https://www.investorideas.com/News-Upload/ and tickertagstocknews.com
Global investors must adhere to regulations of each country. Please read Investorideas.com privacy policy: https://www.investorideas.com/About/Private_Policy.asp

Learn more about our news, PR and social media services at Investorideas.com

Follow us on Twitter https://twitter.com/Investorideas
Download our Mobile App for iPhone and Android  

To sponsor a daily podcast for the month or to be an expert guest please contact us!

Contact Investorideas.com
800-665-0411