Biotech/Pharma Companies Targeting Pancreatic Cancer: (SBFM), (NLNK), (LLY, NYSE), (CELG)

Point Roberts, WA, New York, NY - February 26, 2014 (Investorideas.com Biotech Newswire) Investorideas.com global news source covering leading sectors including biotech and pharma reports on companies in the sector targeting pancreatic cancer. Companies include NewLink Genetics (NLNK), Sunshine Biopharma Inc. ( OTCBB: SBFM ), Eli Lilly and Company (NYSE: LLY) and Celgene (NASDAQ::CELG).

According to the Pancreatic Cancer Action Network "Pancreatic cancer is currently the fourth leading cause of cancer death in the United States, and is anticipated to become the second by 2020.”
In their fact sheet they also note " Pancreatic cancer is one of the nation's deadliest cancers with a five-year relative survival rate of just 6 percent. An estimated 73 percent of patients will die in the first year of diagnosis. In 2014, an estimated 46,420 people will be diagnosed with pancreatic cancer in the United States, and approximately 39,590 will die from the disease.”
Decision Resources (http://www.decisionresources.com/),one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that the pancreatic cancer therapy market will nearly double to $1.3 billion in 2022, owing to the launch and rapid uptake of three high-priced agents—Celgene (NASDAQ::CELG)/Taiho's Abraxane, Onconova Therapeutics/Baxter International/SymBio Pharmaceuticals' Estybon and Merrimack Pharmaceuticals' MM-398 (a novel formulation of irinotecan). Even though these agents do not substantially improve the overall survival of pancreatic cancer patients, they will have a significant impact on current treatment.
The Pharmacor Pancreatic Cancer report also finds that significant commercial reward awaits developers of therapies that are more effective and better tolerated than the FOLFIRINOX regimen in this disease, as the need for efficacious, well-tolerated therapies will remain through 2022.
NewLink Genetics (NASDAQ: NLNK) has been of the top gainers for 2014,gaining over 90%.NewLink's portfolio includes biologic and small molecule immunotherapy product candidates intended to treat a wide range of oncology indications.
Their product, RAlgenpantucel-L is an investigational HyperAcute™ immunotherapy for pancreatic cancer. The product consists of 2 pancreatic cancer cell lines (HAPa-1 and HAPa-2) that have been genetically modified to express alpha-gal carbohydrates on cell surface molecules.1 Upon injection into the patient, the alpha-gal stimulates an immune response against pancreatic cancer-specific antigens in the tumor cell lines. The patient's immune system then targets its own pancreatic cancer cells, destroying them.1 In the adjuvant setting, the immune response targets and eradicates residual tumor cells in conjunction with chemotherapy and chemoradiation.1,2
Algenpantucel-L is currently being studied in combination with standard of care in two phase 3 trials:
Last fall the company reported greater than expected responses to follow-on chemotherapy after treatment with algenpantucel-L or tergenpumatucel-L HyperAcute immunotherapy. Three pancreatic cancer patients were followed for response to subsequent salvage chemotherapy treatment after progressing on algenpantucel-L therapy. All three patients experienced durable (12-36 months), complete responses.
Sunshine Biopharma Inc. ( OTCBB: SBFM ), a pharmaceutical company focused on the research, development and commercialization of drugs for the treatment of various forms of cancer, recently announced that it is targeting pancreatic cancer as second indication for its leading compound, Adva-27a.
As previously announced, Adva-27a was found to be effective at killing Pancreatic Cancer Cells in vitro. Based on initial data, the company is now advancing research using Adva-27a for pancreatic cancer treatment.
The initial study, as reported in June 2013, was carried out in the very aggressive Pancreatic Cancer cell line, Panc-1. Adva-27a was able to kill these cells with an IC50 of less than 4 micromolar, a pharmacologically very favorable drug concentration.
Adva-27a is Sunshine Biopharma's lead anticancer compound, a small molecule that has recently been shown to be effective at killing multidrug resistant breast cancer cells, small-cell lung cancer cells, uterine sarcoma cells and pancreatic cancer cells (Published in ANTICANCER RESEARCH, Volume 32, Pages 4423-4432, October 2012). Adva-27a is currently in the IND-Enabling stage of development. The original U.S. patent covering Adva-27a was issued on August 7, 2012 under US patent number 8,236,935.
The Company also announced that it has initiated the construction of mouse xenograft models for pancreatic cancer as part of the plans of positioning Adva-27a for clinical development for pancreatic cancer in parallel with multidrug resistant breast cancer. The work is being conducted in collaboration with Sunshine Biopharma's parent company, Advanomics Corporation, the co-recipient of $1.45 million in research grants in Canada. As previously announced (see press release dated June 4, 2013), Adva-27a, a Topoisomerase II inhibitor, was found to be effective at destroying cells of the very aggressive pancreatic cancer cell line, Panc-1.
"Conducting tests in pancreatic cancer xenograft models is the next step in our preparations for doing parallel breast cancer and pancreatic cancer clinical trials of Adva-27a," said Dr. Steve N. Slilaty, Chief Executive Officer of Sunshine Biopharma. "Pancreatic cancer is an extremely aggressive form of cancer with essentially no effective treatment options available today. We are heartened by the prospects that Adva-27a could become an effective therapy for patients suffering this deadly form of cancer."
According to Global Industry Analysts, Inc. in their recent report, "Eli Lilly's (LLY:NYSE) Gemzar (Gemcitabine) is the current gold standard of care for locally advanced and metastatic disease, with a dominance that is undisputed despite a median survival of less than 6 months and rate of one-year survival of around 18%, as stated by the new market research report on Pancreatic cancer drugs. Though the odds of survival are somewhat better in other forms of cancer, the rate of five-year survival for the most common form of pancreatic cancer, Adenocarcinoma of the pancreas is less than 5%, with majority of patients surviving just a few months. "
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BC Residents and Investor Disclaimer: Effective September 15 2008 - all BC investors should review all OTC and Pink sheet listed companies for adherence in new disclosure filings and filing appropriate documents with Sedar. Read for more info: http://www.bcsc.bc.ca/release.aspx?id=6894. Global investors must adhere to regulations of each country.
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Biotech/Pharma Companies Targeting Pancreatic Cancer: (SBFM), (NLNK), (LLY), (CELG)

Point Roberts WA, New York, NY - February 19, 2014 (Investorideas.com Biotech Newswire) Investorideas.com global news source covering leading sectors including biotech and pharma reports on companies in the sector targeting pancreatic cancer. Stocks mentioned include NewLink Genetics (NLNK), Sunshine Biopharma Inc. ( OTCBB: SBFM ), Eli Lilly and Company (NYSE:LLY) and Celgene (NASDAQ:CELG).

Decision Resources ( http://www.decisionresources.com/ ),one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that the pancreatic cancer therapy market will nearly double to $1.3 billion in 2022, owing to the launch and rapid uptake of three high-priced agents-Celgene (NASDAQ:CELG)/Taiho's Abraxane, Onconova Therapeutics/Baxter International/SymBio Pharmaceuticals' Estybon and Merrimack Pharmaceuticals' MM-398 (a novel formulation of irinotecan). Even though these agents do not substantially improve the overall survival of pancreatic cancer patients, they will have a significant impact on current treatment.
The Pharmacor Pancreatic Cancer report also finds that significant commercial reward awaits developers of therapies that are more effective and better tolerated than the FOLFIRINOX regimen in this disease, as the need for efficacious, well-tolerated therapies will remain through 2022.
NewLink Genetics (NASDAQ:NLNK) has been of the top gainers for 2014,gaining over 90%.NewLink's portfolio includes biologic and small molecule immunotherapy product candidates intended to treat a wide range of oncology indications.
Their product, RAlgenpantucel-L is an investigational HyperAcute™ immunotherapy for pancreatic cancer. The product consists of 2 pancreatic cancer cell lines (HAPa-1 and HAPa-2) that have been genetically modified to express alpha-gal carbohydrates on cell surface molecules.1 Upon injection into the patient, the alpha-gal stimulates an immune response against pancreatic cancer-specific antigens in the tumor cell lines. The patient’s immune system then targets its own pancreatic cancer cells, destroying them.1 In the adjuvant setting, the immune response targets and eradicates residual tumor cells in conjunction with chemotherapy and chemoradiation.1,2.
Algenpantucel-L is currently being studied in combination with standard of care in two phase 3 trials:
Last fall the company reported greater than expected responses to follow-on chemotherapy after treatment with algenpantucel-L or tergenpumatucel-L HyperAcute immunotherapy. Three pancreatic cancer patients were followed for response to subsequent salvage chemotherapy treatment after progressing on algenpantucel-L therapy. All three patients experienced durable (12-36 months), complete responses.
Sunshine Biopharma Inc. ( OTCBB:SBFM ), a pharmaceutical company focused on the research, development and commercialization of drugs for the treatment of various forms of cancer, recently announced that it is targeting pancreatic cancer as second indication for its leading compound, Adva-27a.
As previously announced, Adva-27a was found to be effective at killing Pancreatic Cancer Cells in vitro. Based on initial data, the company is now advancing research using Adva-27a for pancreatic cancer treatment.
The initial study, as reported in June 2013, was carried out in the very aggressive Pancreatic Cancer cell line, Panc-1. Adva-27a was able to kill these cells with an IC50 of less than 4 micromolar, a pharmacologically very favorable drug concentration.
Adva-27a is Sunshine Biopharma's lead anticancer compound, a small molecule that has recently been shown to be effective at killing multidrug resistant breast cancer cells, small-cell lung cancer cells, uterine sarcoma cells and pancreatic cancer cells (Published in ANTICANCER RESEARCH, Volume 32, Pages 4423-4432, October 2012). Adva-27a is currently in the IND-Enabling stage of development. The original U.S. patent covering Adva-27a was issued on August 7, 2012 under US patent number 8,236,935.
According to Global Industry Analysts, Inc. in their recent report, "Eli Lilly's (NYSE:LLY) Gemzar (Gemcitabine) is the current gold standard of care for locally advanced and metastatic disease, with a dominance that is undisputed despite a median survival of less than 6 months and rate of one-year survival of around 18%, as stated by the new market research report on Pancreatic cancer drugs. Though the odds of survival are somewhat better in other forms of cancer, the rate of five-year survival for the most common form of pancreatic cancer, Adenocarcinoma of the pancreas is less than 5%, with majority of patients surviving just a few months. "
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Disclaimer/ Disclosure: The Investorideas.com newswire is a third party publisher of news and research as well as creates original content as a news source. Original content created by investor ideas is protected by copyright laws other than syndication rights. Investor ideas is a news source on Google news and Linkedintoday plus hundreds of syndication partners. Our site does not make recommendations for purchases or sale of stocks or products. Nothing on our sites should be construed as an offer or solicitation to buy or sell products or securities. All investment involves risk and possible loss of investment. This site is currently compensated by featured companies, news submissions, content marketing and online advertising. Contact each company directly for press release questions. Disclosure is posted on each release if required but otherwise the news was not compensated for and is published for the sole interest of our readers. More disclaimer info: http://www.investorideas.com/About/Disclaimer.asp Disclosure investor ideas has been compensated with 144 shares for news and content publication ( 100,000 per three month period)
BC Residents and Investor Disclaimer : Effective September 15 2008 - all BC investors should review all OTC and Pink sheet listed companies for adherence in new disclosure filings and filing appropriate documents with Sedar. Read for more info: http://www.bcsc.bc.ca/release.aspx?id=6894. Global investors must adhere to regulations of each country.
800-665-0411 -   Source – www.Investorideas.com

Biotech News Alert: SUNSHINE BIOPHARMA (OTCQB: SBFM) BEGINS CONSTRUCTION OF MOUSE XENOGRAFT MODELS FOR PANCREATIC CANCER TO ADVANCE Adva-27a AS A TREATMENT FOR THIS DEADLY FORM OF CANCER

Montreal, Quebec, Canada - February 14, 2014 (Investorideas.com Biotech Newswire) Biopharma alert: Sunshine Biopharma Inc. (OTCQB: SBFM), a pharmaceutical company focused on the research, development and commercialization of drugs for the treatment of various forms of cancer, today announced that it has initiated the construction of mouse xenograft models for pancreatic cancer as part of the plans of positioning Adva-27a for clinical development for pancreatic cancer in parallel with multidrug resistant breast cancer. The work is being conducted in collaboration with Sunshine Biopharma’s parent company, Advanomics Corporation, the co-recipient of $1.45 million in research grants in Canada. As previously announced (see press release dated June 4, 2013), Adva-27a, a Topoisomerase II inhibitor, was found to be effective at destroying cells of the very aggressive pancreatic cancer cell line, Panc-1.

"Conducting tests in pancreatic cancer xenograft models is the next step in our preparations for doing parallel breast cancer and pancreatic cancer clinical trials of Adva-27a," said Dr. Steve N. Slilaty, Chief Executive Officer of Sunshine Biopharma. "Pancreatic cancer is an extremely aggressive form of cancer with essentially no effective treatment options available today. We are heartened by the prospects that Adva-27a could become an effective therapy for patients suffering this deadly form of cancer."
About Pancreatic Cancer
Pancreatic cancer has an extremely poor prognosis. Most pancreatic cancer patients will die within one year of diagnosis. Cancer of the pancreas is the fourth most common cause of cancer-related deaths in the United States. According to the American Cancer Society, an estimated 45,220 new cases of pancreatic cancer will be diagnosed in the U.S. in 2013. Approximately 95% of pancreatic tumors are of the adenocarcinoma type, arising within the exocrine component of the pancreas where various digestive enzymes are produced. The remaining 5% arise from the islet cells and are classified as neuroendocrine tumors. The islet cells produce important hormones such as insulin, which regulates the sugar levels in the blood. Both types are very aggressive and respond poorly to standard chemotherapy drugs. In contrast to the downward trend in death rates for most major cancer types, death rates due to pancreatic cancer have been slowly increasing in the U.S. over the past decade. This, together with the lack effective therapy, underscores the need for major new drug development efforts to reverse these trends.
About Adva-27a
Adva-27a is Sunshine Biopharma's lead anticancer compound, a small molecule that has recently been shown to be effective at killing multidrug resistant breast cancer cells, small-cell lung cancer cells, uterine sarcoma cells and pancreatic cancer cells (Published in ANTICANCER RESEARCH, Volume 32, Pages 4423-4432, October 2012). Adva-27a is currently in the IND-Enabling stage of development. The original U.S. patent covering Adva-27a was issued on August 7, 2012 under U.S. patent number 8,236,935.
About Sunshine Biopharma Inc.
Sunshine Biopharma is an early stage pharmaceutical company focused on the research, development and commercialization of drugs for the treatment of various forms of cancer. Sunshine Biopharma recently announced that it has initiated IND-Enabling studies for its lead antitumor compound, Adva-27a, which is currently targeted for multidrug resistant cancer.
Safe Harbor Forward-Looking Statements
To the extent that statements in this press release are not strictly historical, including statements as to revenue projections, business strategy, outlook, objectives, future milestones, plans, intentions, goals, future financial conditions, future collaboration agreements, the success of the Company's development, events conditioned on stockholder or other approval, or otherwise as to future events, such statements are forward-looking, and are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. The forward-looking statements contained in this release are subject to certain risks and uncertainties that could cause actual results to differ materially from the statements made.
For Additional Information Contact:
Camille Sebaaly, CFO
Sunshine Biopharma Inc.
Direct Line: 514-814-0464
camille.sebaaly@sunshinebiopharma.com
www.sunshinebiopharma.com
Disclaimer/ Disclosure:The Investorideas.com newswire is a third party publisher of news and research as well as creates original content as a news source. Original content created by investorideas is protected by copyright laws other than syndication rights. Investorideas is a news source on Google news and Linkedintoday plus hundreds of syndication partners. Our site does not make recommendations for purchases or sale of stocks or products. Nothing on our sites should be construed as an offer or solicitation to buy or sell products or securities. All investment involves risk and possible loss of investment. This site is currently compensated by featured companies, news submissions, content marketing and online advertising. Contact each company directly for press release questions. Disclosure is posted on each release if required but otherwise the news was not compensated for and is published for the sole interest of our readers. Disclosure: SBFM has renewed effective December 3,2013 with Investorideas for six months of news publication and general public awareness of the company news and technologies and products in the biopharma markets ( one hundred thousand shares of 144 stock per 3 month period for a total of six months ) More disclaimer info: http://www.investorideas.com/About/Disclaimer.aspBC Residents and Investor Disclaimer: Effective September 15 2008 - all BC investors should review all OTC and Pink sheet listed companies for adherence in new disclosure filings and filing appropriate documents with Sedar. Read for more info: http://www.bcsc.bc.ca/release.aspx?id=6894. Global investors must adhere to regulations of each country.

Biotech News Alert: SUNSHINE BIOPHARMA (OTCQB: SBFM) CONTINUES ITS EFFORTS TO RE-DOMICILE IN CANADA FOR BUSINESS EXPANSION AND FINANCING OPPORTUNITIES FOR Adva-27a CANCER DRUG CANDIDATE

Montreal, Quebec, Canada - February 4, 2014 (Investorideas.com Biotech Newswire) Biopharma alert: Sunshine Biopharma Inc. (OTCQB: SBFM), a pharmaceutical company focused on the research, development and commercialization of proprietary drugs for the treatment of various forms of cancer, today announced that it is continuing its efforts to re-domiciling the Company in Canada in order to capitalize on management’s belief that by doing so, the Company will generate additional business expansion opportunities and gain access to financing programs available to Canadian corporations. On January 31, 2014, the Company filed an S-4 Registration Statement wherein it is attempting to re-domicile to Canada from Colorado.

"We are very pleased with the progress we have made thus far in our efforts to re-domicile the Company in Canada," said Dr. Steve N. Slilaty, Chief Executive Officer of Sunshine Biopharma. "We are anxious to complete the re-domiciling process as we have attendant growth and financing opportunities that we believe are available to us once we have completed this action. This is important for the Company’s business strategy overall and for our Adva-27a anticancer drug candidate as we advance towards clinical trials for multidrug resistant breast cancer and pancreatic cancer."
About Adva-27a
Adva-27a is Sunshine Biopharma's lead anticancer compound, a small molecule that has recently been shown to be effective at killing multidrug resistant breast cancer cells, small-cell lung cancer cells, uterine sarcoma cells and pancreatic cancer cells (Published in ANTICANCER RESEARCH, Volume 32, Pages 4423-4432, October 2012). Adva-27a is currently in the IND-Enabling stage of development. The original U.S. patent covering Adva-27a was issued on August 7, 2012 under U.S. patent number 8,236,935.
About Sunshine Biopharma Inc.
Sunshine Biopharma is an early stage pharmaceutical company focused on the research, development and commercialization of drugs for the treatment of various forms of cancer. Sunshine Biopharma recently announced that it has initiated IND-Enabling studies for its lead antitumor compound, Adva-27a, which is currently targeted for multidrug resistant cancer.
Safe Harbor Forward-Looking Statements
To the extent that statements in this press release are not strictly historical, including statements as to revenue projections, business strategy, outlook, objectives, future milestones, plans, intentions, goals, future financial conditions, future collaboration agreements, the success of the Company's development, events conditioned on stockholder or other approval, or otherwise as to future events, such statements are forward-looking, and are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. The forward-looking statements contained in this release are subject to certain risks and uncertainties that could cause actual results to differ materially from the statements made.
For Additional Information Contact:
Camille Sebaaly, CFO
Sunshine Biopharma Inc.
Direct Line: 514-814-0464
camille.sebaaly@sunshinebiopharma.com
www.sunshinebiopharma.com
Disclaimer/ Disclosure:The Investorideas.com newswire is a third party publisher of news and research as well as creates original content as a news source. Original content created by investorideas is protected by copyright laws other than syndication rights. Investorideas is a news source on Google news and Linkedintoday plus hundreds of syndication partners. Our site does not make recommendations for purchases or sale of stocks or products. Nothing on our sites should be construed as an offer or solicitation to buy or sell products or securities. All investment involves risk and possible loss of investment. This site is currently compensated by featured companies, news submissions, content marketing and online advertising. Contact each company directly for press release questions. Disclosure is posted on each release if required but otherwise the news was not compensated for and is published for the sole interest of our readers. Disclosure: SBFM has renewed effective December 3,2013 with Investorideas for six months of news publication and general public awareness of the company news and technologies and products in the biopharma markets ( one hundred thousand shares of 144 stock per 3 month period for a total of six months ) More disclaimer info: http://www.investorideas.com/About/Disclaimer.aspBC Residents and Investor Disclaimer: Effective September 15 2008 - all BC investors should review all OTC and Pink sheet listed companies for adherence in new disclosure filings and filing appropriate documents with Sedar. Read for more info: http://www.bcsc.bc.ca/release.aspx?id=6894. Global investors must adhere to regulations of each country.

TSX Biotech Alert: Quest PharmaTech (TSXV: QPT.V) Announces Third Combinatorial Immunotherapy Clinical Trial for Oregovomab with a TLR3 agonist, Hiltonol®

EDMONTON - January 29, 2014 (Investorideas.com Newswire) Quest PharmaTech Inc. (TSXV: QPT.V) ("Quest" or the "Company"), a pharmaceutical company developing and commercializing products for the treatment of cancer, announced today that is has entered into a license agreement with U.S. based Oncovir, Inc. ( Washington, DC ) to evaluate the clinical utility of combining Quest's antibody immunotherapy technology with Oncovir's immune activator "Hiltonol®" in a twenty patient ovarian cancer Phase II clinical trial.

The trial will be conducted in Rome, Italy under the direction of Professor Roberto Angioli of University Bio Medico. Oncovir will provide the needed drug, appropriate technical expertise and relevant data to support the regulatory process necessary to conduct the clinical trial.
Hiltonol® (Poly ICLC) is a TLR-3 agonist that has been shown to have specific anti-tumor and anti-viral actions. It is emerging as a promising component to enhance activity of multiple cancer and HIV vaccines. As a result, Oncovir currently has over two dozen recently completed or ongoing Phase I or II investigator initiated, collaborative clinical trials, using Hiltonol® alone or in combination with other agents. Several hundred patients have been safely treated to date and another dozen trials are in various stages of planning or submission.
This planned clinical study is part of Quest's strategy of conducting three risk mitigating clinical trials with Oregovomab in combination with chemotherapy to confirm its ability to generate a clinically meaningful antigen specific T-cell response in both ovarian cancer patients, and also other CA125 associated cancer settings, such as select patients with pancreatic cancer. Quest seeks to optimize the utility of cancer immunotherapy through artful combination of its antibodies with cytotoxic agents and promising additional immune adjuvants. The first two clinical trials in this initiative are already underway at clinical centers in Italy and the U.S.
"This collaborative clinical study is indicative of our progression as a cancer immunotherapy company and our focused interest in capitalizing on the growing understanding of cancer immunology to enhance the clinical potential of our antibody products. We look forward to working with Oncovir in the conduct of this important clinical trial combining Hiltonol® with Oregovomab", said Dr. Madi R. Madiyalakan , Quest's Chief Executive Officer.
Corporate Update
In other news, Quest announces that it has closed a previously announced non-brokered private placement of $1,000,000 . The private placement was made to Mr. Hong-Gul Cheong , a resident of South Korea , and to AD Biotech Co., Ltd., a Korean company controlled by Mr. Cheong. The shares issued have a four month hold period expiring May 24, 2014. The details of the transaction are in our news release dated November 21, 2013 . Pursuant to the investment agreement approved by our shareholders during our 2012 Annual General Meeting, the Company has so far received a total of $3.65 Million out of an anticipated $12 Million .
Quest also announces that Dr. Madiyalakan will be attending the Bio CEO Conference to be held in New York , February 10 and 11, 2014.
About Quest PharmaTech Inc.
Quest PharmaTech is a publicly traded, Canadian based clinical stage company developing a portfolio of product candidates for the treatment of cancer by combining immunotherapeutic antibodies with chemotherapy, immune-adjuvants and photodynamic therapy. Quest has a body of clinical experience and a new appreciation of the obstacles and potential of combinatorial immunotherapeutic approaches to cancer by using either immunoglobulin G or E as immune modulators to enhance tumor specific immunity and clinical outcome.
The most advanced of its product candidates is oregovomab, an anti-CA125 monoclonal antibody, in combination with front-line chemotherapy for the treatment of advanced ovarian cancer which is currently undergoing a phase IIb clinical trial in 12 centers in Italy and the U.S. The Company's MUC1 program that has already undergone a phase I clinical trial has the potential to permit tumor specific immunization in more than 70% of all cancers that kill. Quest is also conducting a phase I clinical trial for the treatment of prostate cancer, with its photosensitizer, SL052.
Neither TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.
SOURCE Quest PharmaTech Inc.
Contact:
Dr. Madi R. Madiyalakan, Chief Executive Officer, Quest PharmaTech Inc., Tel: (780) 448-1400 Ext. 204, Email: madi@questpharmatech.com, Internet: www.questpharmatech.com
Published at Investorideas.com newswire
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Disclaimer/ Disclosure: The Investorideas.com newswire is a third party publisher of news and research as well as creates original content as a news source. Original content created by investorideas is protected by copyright laws other than syndication rights. Investorideas is a news source on Google news and Linkedintoday plus hundreds of syndication partners. Our site does not make recommendations for purchases or sale of stocks or products. Nothing on our sites should be construed as an offer or solicitation to buy or sell products or securities. All investment involves risk and possible loss of investment. This site is currently compensated by featured companies, news submissions, content marketing and online advertising. Contact each company directly for press release questions. Disclosure is posted on each release if required but otherwise the news was not compensated for and is published for the sole interest of our readers. Disclosure: QPT.V, a public company, has engaged Investorideas.com for public relations services for four thousand a month retainer fee.

Biotech News Alert: SUNSHINE BIOPHARMA (OTCQB: SBFM) EXPANDS DRUG PIPELINE TARGETING PANCREATIC CANCER AS SECOND INDICATION FOR CLINICAL TRIALS OF Adva-27a COMPOUND

Montreal, Quebec, Canada - January 22, 2014 (Investorideas.com Biotech Newswire) Biopharma alert: Sunshine Biopharma Inc. (OTCQB: SBFM), a pharmaceutical company focused on the research, development and commercialization of drugs for the treatment of various forms of cancer, reports that it is targeting pancreatic cancer as a second indication for Adva-27a, the Company’s flagship anticancer drug candidate. As previously announced (see press release dated June 4, 2013), Adva-27a, a Topoisomerase II inhibitor, was found to be effective at destroying cells of the very aggressive pancreatic cancer cell line, Panc-1. Adva-27a was able to kill these cells with an IC50 of approximately 4 micromolar, a pharmacologically very favorable drug concentration. Based on initial data, the Company is moving forward with intentions to conduct a Phase I clinical trial of Adva-27a for pancreatic cancer in parallel to the planned Phase I clinical trial of Adva-27a for breast cancer that is scheduled to be hosted at McGill University's Jewish General Hospital in Montreal.

Full news: http://www.investorideas.com/CO/SBFM/news/2014/01211.asp
January 21 st Close : $0.20 Up 0.03(14.29%)
About Adva-27a
Adva-27a is Sunshine Biopharma's lead anticancer compound, a small molecule that has recently been shown to be effective at killing multidrug resistant breast cancer cells, small-cell lung cancer cells, uterine sarcoma cells and pancreatic cancer cells (Published in ANTICANCER RESEARCH, Volume 32, Pages 4423-4432, October 2012). Adva-27a is currently in the IND-Enabling stage of development. The original U.S. patent covering Adva-27a was issued on August 7, 2012 under U.S. patent number 8,236,935.
About Sunshine Biopharma Inc.
Sunshine Biopharma is an early stage pharmaceutical company focused on the research, development and commercialization of drugs for the treatment of various forms of cancer. Sunshine Biopharma recently announced that it has initiated IND-Enabling studies for its lead antitumor compound, Adva-27a, which is currently targeted for multidrug resistant cancer.
Safe Harbor Forward-Looking Statements
To the extent that statements in this press release are not strictly historical, including statements as to revenue projections, business strategy, outlook, objectives, future milestones, plans, intentions, goals, future financial conditions, future collaboration agreements, the success of the Company's development, events conditioned on stockholder or other approval, or otherwise as to future events, such statements are forward-looking, and are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. The forward-looking statements contained in this release are subject to certain risks and uncertainties that could cause actual results to differ materially from the statements made.
For Additional Information Contact:
Camille Sebaaly, CFO
Sunshine Biopharma Inc.
Direct Line: 514-814-0464
camille.sebaaly@sunshinebiopharma.com
www.sunshinebiopharma.com
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Biotech News Alert: Sunshine Biopharma (OTCQB: SBFM) Targets Pancreatic Cancer as Second Indication for Clinical Trials of Adva-27a Compound

MONTREAL, QC - January 21, 2014 (Investorideas.com Biotech Newswire) Sunshine Biopharma Inc. ( OTCQB: SBFM ), a pharmaceutical company focused on the research, development and commercialization of drugs for the treatment of various forms of cancer, today announced that it is now targeting pancreatic cancer as a second indication for Adva-27a, the Company's flagship anticancer drug candidate. As previously announced (see press release dated June 4, 2013), Adva-27a, a Topoisomerase II inhibitor, was found to be effective at destroying cells of the very aggressive pancreatic cancer cell line, Panc-1. Adva-27a was able to kill these cells with an IC50 of approximately 4 micromolar, a pharmacologically very favorable drug concentration. Based on initial data, the Company is moving forward with intentions to conduct a Phase I clinical trial of Adva-27a for pancreatic cancer in parallel to the planned Phase I clinical trial of Adva-27a for breast cancer that is scheduled to be hosted at McGill University's Jewish General Hospital in Montreal.

"As we work towards completing the process of re-domiciling the Company to Canada and conducting the requisite IND-enabling toxicology studies of Adva-27a, we are now proceeding with additional research centered on pancreatic cancer as a second indication," said Dr. Steve N. Slilaty, Chief Executive Officer of Sunshine Biopharma. "Pancreatic cancer represents an area of tremendous unmet medical need and significant market opportunity. Our research to date indicates that Adva-27a has the potential to become a new therapy option for patients suffering this deadly form of cancer."
About Pancreatic Cancer
Pancreatic cancer has an extremely poor prognosis. Most pancreatic cancer patients will die within one year of diagnosis. Cancer of the pancreas is the fourth most common cause of cancer-related deaths in the United States. According to the American Cancer Society, an estimated 45,220 new cases of pancreatic cancer will be diagnosed in the U.S. in 2013. Approximately 95% of pancreatic tumors are of the adenocarcinoma type, arising within the exocrine component of the pancreas where various digestive enzymes are produced. The remaining 5% arise from the islet cells and are classified as neuroendocrine tumors. The islet cells produce important hormones such as insulin, which regulates the sugar levels in the blood. Both types are very aggressive and respond poorly to standard chemotherapy drugs. In contrast to the downward trend in death rates for most major cancer types, death rates due to pancreatic cancer have been slowly increasing in the U.S. over the past decade. This, together with the lack effective therapy, underscores the need for major new drug development efforts to reverse these trends.
About Adva-27a
Adva-27a is Sunshine Biopharma's lead anticancer compound, a small molecule that has recently been shown to be effective at killing multidrug resistant breast cancer cells, small-cell lung cancer cells, uterine sarcoma cells and pancreatic cancer cells (Published in ANTICANCER RESEARCH, Volume 32, Pages 4423-4432, October 2012). Adva-27a is currently in the IND-Enabling stage of development. The original U.S. patent covering Adva-27a was issued on August 7, 2012 under U.S. patent number 8,236,935.
About Sunshine Biopharma Inc.
Sunshine Biopharma is an early stage pharmaceutical company focused on the research, development and commercialization of drugs for the treatment of various forms of cancer. Sunshine Biopharma recently announced that it has initiated IND-Enabling studies for its lead antitumor compound, Adva-27a, which is currently targeted for multidrug resistant cancer.
Safe Harbor Forward-Looking Statements
To the extent that statements in this press release are not strictly historical, including statements as to revenue projections, business strategy, outlook, objectives, future milestones, plans, intentions, goals, future financial conditions, future collaboration agreements, the success of the Company's development, events conditioned on stockholder or other approval, or otherwise as to future events, such statements are forward-looking, and are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. The forward-looking statements contained in this release are subject to certain risks and uncertainties that could cause actual results to differ materially from the statements made.
For Additional Information Contact:
Camille Sebaaly, CFO
Sunshine Biopharma Inc.
Direct Line: 514-814-0464
camille.sebaaly@sunshinebiopharma.com
www.sunshinebiopharma.com
Disclaimer/ Disclosure:The Investorideas.com newswire is a third party publisher of news and research as well as creates original content as a news source. Original content created by investorideas is protected by copyright laws other than syndication rights. Investorideas is a news source on Google news and Linkedintoday plus hundreds of syndication partners. Our site does not make recommendations for purchases or sale of stocks or products. Nothing on our sites should be construed as an offer or solicitation to buy or sell products or securities. All investment involves risk and possible loss of investment. This site is currently compensated by featured companies, news submissions, content marketing and online advertising. Contact each company directly for press release questions. Disclosure is posted on each release if required but otherwise the news was not compensated for and is published for the sole interest of our readers. Disclosure: SBFM has renewed effective December 3,2013 with Investorideas for six months of news publication and general public awareness of the company news and technologies and products in the biopharma markets ( one hundred thousand shares of 144 stock per 3 month period for a total of six months ) More disclaimer info: http://www.investorideas.com/About/Disclaimer.asp
BC Residents and Investor Disclaimer: Effective September 15 2008 - all BC investors should review all OTC and Pink sheet listed companies for adherence in new disclosure filings and filing appropriate documents with Sedar. Read for more info: http://www.bcsc.bc.ca/release.aspx?id=6894. Global investors must adhere to regulations of each country.