Recent Biotech IPO’s; (ASND), (ENTL), (FLKS), (ONCE), (TCON), (ZSAN)

Recent Biotech IPO’s; (ASND), (ENTL), (FLKS), (ONCE), (TCON), (ZSAN)

Point Roberts WA, NEW YORK, NY – February 3, 2015 - Investorideas.com, a global news source covering leading sectors including biotech and medical technology stocks reports on the recent IPO’s in the sector. The flood of IPO’s is making experts ask if a biotech bubble is being created. With up to 100 IPO’s in the works for this year, time will tell.

Here is a look at some of the recent listings:

Ascendis Pharma (NASDAQ:ASND) completed its initial public offering of 6,900,000 American Depositary Shares (ADSs) at a price to the public of $18.00 per ADS. The stock is currently trading at $19.04. Ascendis Pharma A/S is a clinical stage biopharmaceutical company applying its TransCon technology to develop a pipeline of long-acting prodrug therapies with best-in-class profiles to address large markets with significant unmet medical needs.

Entellus Medical Inc (NASDAQ:ENTL) began trading on The NASDAQ Stock Market on January 29, 2015. The IPO consisted of 4,603,580 shares of its common stock at an initial public offering price of $17.00 per share Entellus is a medical technology company focused on the design, development and commercialization of products for the minimally invasive treatment of patients in the physician office setting or operating room who are suffering from chronic sinusitis. The XprESS family of products is used by ear, nose and throat, or ENT, physicians to open narrowed or obstructed sinus drainage pathways using balloon sinus dilation to treat patients with symptomatic inflammation of the nasal sinuses. The stock is currently trading at $21.52.

On January 28^th Flex Pharma Inc (NASDAQ: FLKS) announced its initial public offering of 5,400,000 shares of common stock at a public offering price of $16.00 per share. Flex Pharma, Inc. is a biopharmaceutical company that is developing innovative and proprietary treatments for nocturnal leg cramps and spasms associated with severe neuromuscular conditions.

January 30^th Spark Therapeutics Inc (NASDAQ:ONCE)  announced its offering of 7,000,000 shares of common stock at a public offering price of $23.00 per share, before underwriting discounts. Spark is a late clinical-stage gene therapy company seeking to develop one-time, life-altering treatments for debilitating genetic diseases, with an initial focus on treating rare diseases. Spark's most advanced product candidate, SPK-RPE65, which has received both breakthrough therapy and orphan product designation, is in a fully-enrolled pivotal Phase 3 clinical trial for the treatment of a rare blinding condition. Spark also has product candidates in development for the treatment of additional blinding conditions, hematologic disorders and neurodegenerative diseases. The stock is trading at $45.82 this morning.

TRACON Pharmaceuticals Inc (NASDAQ:TCON) IPO consisted of 3,600,000 shares of common stock at a price to the public of $10.00 per share. TRACON develops targeted therapies for cancer, age‐related macular degeneration and fibrotic diseases. TRACON’s current pipeline includes two clinical stage product candidates: TRC105, an antiendoglin antibody that is being developed for the treatment of multiple solid tumor types, and TRC102, a small molecule that is being developed for the treatment of lung cancer and glioblastoma. Both TRC105 and TRC102 are being developed for treatment in combination with currently available therapies. The stock is currently trading below its IPO price. 

Zosano Pharma Corp (NASDAQ:ZSAN) completed its offering of 4,500,000 shares of common stock at a price to the public of $11.00 per share. The stock is trading at $11.06 in this morning’s session. Zosano Pharma Corporation is a clinical stage specialty pharmaceutical company that has developed a proprietary transdermal microneedle patch system to deliver its proprietary formulations of existing drugs through the skin for the treatment of a variety of indications. Zosano's microneedle patch system offers rapid onset, consistent drug delivery, improved ease of use and room-temperature stability, benefits that the company believes often are unavailable using oral formulations or injections. Zosano's microneedle patch system has the potential to deliver numerous medications for a wide variety of indications in commercially attractive markets. It has been tested in more than 400 patients with over 30,000 patches successfully applied to humans in Phase 1 and Phase 2 clinical studies.

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GenSpera (OTCQB:GNSZ) Presents at BIO CEO & Investor Conference

Biotech News Alert: GenSpera (OTCQB:GNSZ) Presents at BIO CEO & Investor Conference

Company Plans for Multi-Pronged, Long Term Expansion of Novel Treatment Platform

NEW YORK - February 2, 2015 (Investorideas.com Biotech Newswire) GenSpera, Inc. (OTCQB:GNSZ) announced today that Craig Dionne, Ph.D., chief executive officer at GenSpera, will present at the 17th Annual BIO CEO & Investor Conference on February 9th at 1 p.m. at the Waldorf Astoria in New York City. The presentation comes as GenSpera continues clinical development of mipsagargin for several tumor types and expands the applicability of its innovative mechanism of action in a broad array of oncology treatments.

The presentation will provide an update on GenSpera's long-term business growth plans, recent clinical achievements for mipsagargin in the treatment of hepatocellular carcinoma (HCC), and its ongoing Phase II trials in glioblastoma and prostate cancer. Last month, GenSpera presented positive Phase II study results for mipsagargin in treating HCC at the 2015 Gastrointestinal Cancers Symposium in San Francisco, Calif., demonstrating a proof of concept for its intellectual property. A live webcast of the BIO CEO presentation will be broadcast at: http://www.veracast.com/webcasts/bio/ceoinvestor2015/37117595001.cfm.

"We have reached an important milestone with positive Phase II results, which demonstrated that mipsagargin works as designed and destroys established tumor vasculature while sparing patients the debilitating side effects of traditional chemotherapy," said Dionne. "We are confident that this now proven state-of-the-art precision approach has every potential to be a game changer in how we treat cancer."

Mipsagargin's mechanism of action works by targeting the enzyme prostate-specific membrane antigen (PSMA), which is highly expressed in all cancer tumor vasculature and in prostate cancer cells. The Phase II study results presented in San Francisco demonstrated that the prodrug effectively stabilizes progression of HCC by reducing blood flow within tumors while not affecting blood flow within normal tissues. The study also showed indications that patients had improved quality of life and fewer side effects than typically seen in cancer treatment. After successfully demonstrating its proof of concept, GenSpera will move forward with plans to show that mipsagargin is effective across a broad array of tumor indications.

"We are committed to the ongoing development of our technology and working to change the landscape of oncology treatment," continued Dionne. "We believe that the positive clinical results we have observed with mipsagargin will extend to other drug candidates in our portfolio."

Identifying ground-breaking oncology treatments that circumvent side effects, particularly in hard to treat cancers is a key area of oncology research. In the United States, more than 33,000 new cases of HCC will be diagnosed in 2015. Globally, liver cancer is a primary public health issue with more than 700,000 people diagnosed and more than 600,000 deaths annually. There is currently only one approved treatment available for liver cancer.

Additionally, more than 13,000 new cases of glioblastoma are diagnosed in the U.S. each year.

The 17th Annual BIO CEO & Investor Conference is the largest independent investor conference focused on publicly-traded biotechnology companies. The conference is designed to foster an informative dialogue between institutional investors and senior biotechnology executives about emerging and current investment opportunities. The 2014 BIO CEO & Investor Conference featured 1,820 partnering meetings, 149 company presentations and 1,400 attendees, over half of which were investors.

Read this release in full at http://www.investorideas.com/CO/GNSZ/news/2015/02021.asp

About GenSpera

GenSpera Inc. is a San Antonio-based biotech company that unlocks conventional thinking to conceive, design, and develop cancer therapies. GenSpera's technology platform combines a powerful, plant-derived cytotoxin (thapsigargin) with a patented prodrug delivery system that provides for the targeted release of drug candidates within tumors. GenSpera's lead drug candidate, mipsagargin, was granted Orphan Drug designation by the US Food and Drug Administration (FDA) in 2013 for evaluation in patients with hepatocellular carcinoma (liver cancer).

For additional information on GenSpera, visit www.genspera.com and connect on Twitter @GenSperaNews,LinkedIn, Facebook, YouTube and Google+.

Cautionary Statement Regarding Forward Looking Information

This communication may contain forward-looking statements. Investors are cautioned that statements in this document regarding potential applications of GenSpera's technologies or the future prospects of the company constitute forward-looking statements that involve risks and uncertainties, including, without limitation, risks inherent in the development and commercialization of potential products, uncertainty of clinical trial results or regulatory approvals or clearances, need for future capital, dependence upon collaborators and maintenance of our intellectual property rights and the acceptance of GenSpera's proposed therapies by the health community. Actual results may differ materially from the results anticipated in these forward-looking statements. Additional information on potential factors that could affect our results and other risks and uncertainties will be detailed from time to time in GenSpera's periodic reports filed with the Securities and Exchange Commission.

Disclaimer/Disclosure: The Investorideas.com newswire is a third party publisher of news and research as well as creates original content as a news source. Original content created by investorideas is protected by copyright laws other than syndication rights. Investorideas is a news source on Google news and Linkedintoday plus hundreds of syndication partners. Our site does not make recommendations for purchases or sale of stocks or products. Nothing on our sites should be construed as an offer or solicitation to buy or sell products or securities. All investment involves risk and possible loss of investment. This site is currently compensated by featured companies, news submissions, content marketing and online advertising. Contact each company directly for press release questions. Disclosure is posted on each release if required but otherwise the news was not compensated for and is published for the sole interest of our readers. Disclosure: GNSZ is a previous showcase company which expired on December 18, 2014. Investorideas is long 144 shares

BC Residents and Investor Disclaimer: Effective September 15 2008 - all BC investors should review all OTC and Pink sheet listed companies for adherence in new disclosure filings and filing appropriate documents with Sedar. Read for more info: http://www.bcsc.bc.ca/release.aspx?id=6894. Global investors must adhere to regulations of each country.

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GenSpera (OTCQB:GNSZ) Announces Positive Phase II Data for Investigational Agent Mipsagargin

GenSpera (OTCQB:GNSZ) Announces Positive Phase II Data for Investigational Agent Mipsagargin

First-in-Class Agent is Well Tolerated in Liver Cancer Patients

SAN ANTONIO - January 16, 2015 (Investorideas.com Biotech Newswire) GenSpera, Inc. (OTCQB:GNSZ) today announced the encouraging results of a Phase II study of mipsagargin (G-202), an investigational agent for the treatment of hepatocellular carcinoma (HCC). The results will be presented today (12:00 to 2:00 p.m. PST, Abstract #301) in a poster presentation at the 2015 Gastrointestinal Cancers Symposium in San Francisco, California.

The Phase II results demonstrated that mipsagargin appears to be effective and is well-tolerated by HCC patients. Mipsagargin targets the enzyme prostate-specific membrane antigen (PSMA), which is highly expressed in tumor vasculature and prostate cancer cells. The Phase II study results (n=25) demonstrate that the prodrug effectively stabilizes progression of HCC by reducing blood flow within tumors while not affecting blood flow within normal tissues.

"We are very encouraged with the positive results from this Phase II trial that demonstrate the tolerability and show indications of effectiveness of mipsagargin in advanced liver cancer patients," said Craig Dionne, PhD, chief executive officer at GenSpera. "Mipsagargin is a first-in-class agent with a novel mechanism of action that is unlike any other drug being tested in patients with advanced liver cancer. Based on the results of this study, we intend to move forward with a large, global Phase III trial."

Mipsagargin's targeted approach differs from other vascular targeting agents by destroying established tumor vasculature rather than slowing the growth of new tumor blood vessels. The PSMA-targeting agent is designed to minimize side effects commonly observed with other therapies, while maximizing activity against tumors.

"These results demonstrate the potential that mipsagargin has to treat one of the world's deadliest cancers," said Devalingam Mahalingam, MD, PhD, an oncologist at the Cancer Therapy & Research Center at the University of Texas Health Science Center at San Antonio and principal investigator of the study. "In addition to observing prolonged disease stabilization in some patients, we noted anecdotal evidence that patients had improved performance status with much less fatigue and side effects associated with other anti-cancer therapeutics."

With Phase II complete, GenSpera is designing a large, international Phase III study which will further define the anti-tumor potential of mipsagargin in liver cancer patients. More information on mipsagargin (G-202) can be found at www.genspera.com.

Hepatocellular carcinoma is the most common form of cancer that originates in the liver. In the United States, more than 33,000 new cases will be diagnosed in 2015. Globally, liver cancer is a primary public health issue with more than 700,000 people diagnosed and more than 600,000 deaths annually. It is the most common type of cancer in Southeast Asia and sub-Saharan Africa. A liver cancer diagnosis is often subsequent to other liver disease, making treatment of a highly compromised patient population particularly challenging.

Data Establishes Foundation for Continued Investigation

The Phase II study (Abstract #301) of mipsagargin was a multi-site, single arm study designed to assess time to progression and response rate to treatment. The study measured disease progression in 25 patients with advanced-stage liver disease and poor liver reserves who had failed first line treatment with sorafenib. Patients were administered episodic dosing of mipsagargin on the first three days of each treatment cycle. Study participants experienced a median time to progression of 4.2 months, nearly twice the time demonstrated in prior studies with placebo or ineffective agents. Thirty-five percent of patients received 5 or more cycles of treatment with an average time on study of 7.1 months. Additionally, mipsagargin demonstrated decreased blood flow in liver tumors as measured by DCE-MRI.

Read this release in full at http://www.investorideas.com/CO/GNSZ/news/2015/01161.asp

About GenSpera

GenSpera Inc. is a San Antonio-based biotech company that unlocks conventional thinking to conceive, design, and develop cancer therapies. GenSpera's technology platform combines a powerful, plant-derived cytotoxin (thapsigargin) with a patented prodrug delivery system that provides for the targeted release of drug candidates within tumors. GenSpera's lead drug candidate, mipsagargin, was granted Orphan Drug designation by the US Food and Drug Administration (FDA) in 2013 for evaluation in patients with hepatocellular carcinoma (liver cancer).

For additional information on GenSpera, visit www.genspera.com and connect on Twitter @GenSperaNews, LinkedIn, Facebook, YouTube and Google+.

Cautionary Statement Regarding Forward Looking Information

This communication may contain forward-looking statements. Investors are cautioned that statements in this document regarding potential applications of GenSpera's technologies or the future prospects of the company constitute forward-looking statements that involve risks and uncertainties, including, without limitation, risks inherent in the development and commercialization of potential products, uncertainty of clinical trial results or regulatory approvals or clearances, need for future capital, dependence upon collaborators and maintenance of our intellectual property rights and the acceptance of GenSpera's proposed therapies by the health community. Actual results may differ materially from the results anticipated in these forward-looking statements. Additional information on potential factors that could affect our results and other risks and uncertainties will be detailed from time to time in GenSpera's periodic reports filed with the Securities and Exchange Commission.

Disclaimer/Disclosure: The Investorideas.com newswire is a third party publisher of news and research as well as creates original content as a news source. Original content created by investorideas is protected by copyright laws other than syndication rights. Investorideas is a news source on Google news and Linkedintoday plus hundreds of syndication partners. Our site does not make recommendations for purchases or sale of stocks or products. Nothing on our sites should be construed as an offer or solicitation to buy or sell products or securities. All investment involves risk and possible loss of investment. This site is currently compensated by featured companies, news submissions, content marketing and online advertising. Contact each company directly for press release questions. Disclosure is posted on each release if required but otherwise the news was not compensated for and is published for the sole interest of our readers. Disclosure: GNSZ is a previous showcase company which expired on December 18, 2014. Investorideas is long 144 shares

BC Residents and Investor Disclaimer: Effective September 15 2008 - all BC investors should review all OTC and Pink sheet listed companies for adherence in new disclosure filings and filing appropriate documents with Sedar. Read for more info: http://www.bcsc.bc.ca/release.aspx?id=6894. Global investors must adhere to regulations of each country.

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Aethlon Medical (OTCBB: AEMD) to Present at Biotech Showcase 2015

Medical Technology Breaking News: Aethlon Medical (OTCBB: AEMD) to Present at Biotech Showcase 2015

SAN DIEGO - January 8, 2015 (Investorideas.com newswire) Aethlon Medical, Inc. (OTCBB:AEMD), the pioneer in developing targeted therapeutic devices to address infectious diseases and cancer, today announced that James A. Joyce, Chief Executive Officer, will present at the Biotech Showcase 2015 Conference on Wednesday, January 14, 2015.

Details of Aethlon Medical's presentation are as follows:

Event: Biotech Showcase 2015

Date: Wednesday, January 14, 2015

Time: 4:00 p.m. Pacific Time /7:00 p.m. Eastern Time

Location: Parc 55 Wyndham Union Square, San Francisco, CA

A live audio webcast of the presentation will be available on the Company's website (www.aethlonmedical.com) in the Investor Relations section on the Events and Presentations or can be accessed directly at http://edge.media-server.com/m/p/4cvayawf.

The webcast replay will be available approximately two hours after the presentation ends and will be accessible for one month.

About Biotech Showcase 2015

The Biotech Showcase 2015 conference takes place January 12-14, 2015, at the Parc 55 Wyndham Hotel located in Union Square, San Francisco, California. Biotech Showcase is an investor and partnering conference devoted to providing private and public biotechnology and life sciences companies an opportunity to present to, and meet with, investors and pharmaceutical executives during the course of one of the industry's largest annual healthcare investor conferences. Now in its seventh year, Biotech Showcase is expected to attract upwards of 1,500 attendees.

Read this release in full at: http://www.investorideas.com/CO/AEMD/news/2015/01081.asp

About Aethlon Medical, Inc.

Aethlon Medical creates targeted therapeutic devices to address infectious disease, cancer and neurodegenerative disorders. The company's lead product is the Aethlon Hemopurifier®, a first-in-class antiviral and immunotherapeutic device that selectively targets the broad-spectrum elimination of circulating viruses and tumor-secreted exosomes that promote cancer progression. Exosome Sciences, Inc. is a majority owned subsidiary that is advancing exosome-based products to diagnose and monitor cancer, infectious disease and neurological disorders. For more information, please visit http://www.aethlonmedical.com and connect with the Company on Twitter, LinkedIn, Facebook and Google+.

Certain statements herein may be forward-looking and involve risks and uncertainties. Such forward-looking statements involve assumptions, known and unknown risks, uncertainties and other factors which may cause the actual results, performance or achievements of Aethlon Medical, Inc. to be materially different from any future results, performance, or achievements expressed or implied by the forward-looking statements. Such potential risks and uncertainties include, without limitation, that the ESI will not be able to commercialize its future products, that the FDA will not approve the initiation of the Company's clinical programs or provide market clearance of the company's products, future human studies whether revenue or non-revenue generating of the Aethlon ADAPT™ system or the Aethlon Hemopurifier® as an adjunct therapy to improve patient responsiveness to established cancer or hepatitis C therapies or as a standalone cancer or hepatitis C therapy or as a broad spectrum defense against viral pathogens, including ebola, the Company's ability to raise capital when needed, the Company's ability to complete the development of its planned products, the Company's ability to manufacture its products either internally or through outside companies and provide its services, the impact of government regulations, patent protection on the Company's proprietary technology, the ability of the Company to meet the milestones contemplated in the DARPA contract, product liability exposure, uncertainty of market acceptance, competition, technological change, and other risk factors. In such instances, actual results could differ materially as a result of a variety of factors, including the risks associated with the effect of changing economic conditions and other risk factors detailed in the Company's Securities and Exchange Commission filings. The Company undertakes no obligation to publicly update or revise any forward-looking statements, whether as a result of new information, future events, or otherwise.

Contacts:

Leah-Michelle Nebbia (for interview requests) 
Golin 
202-585-2651 
lnebbia@golin.com

James A. Joyce 
Chairman and CEO 
858.459.7800 x301 
jj@aethlonmedical.com

Jim Frakes 
Chief Financial Officer 
858.459.7800 x300 
jfrakes@aethlonmedical.com

Visit this company: www.aethlonmedical.com

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Disclaimer/Disclosure: The Investorideas.com newswire is a third party publisher of news and research as well as creates original content as a news source. Original content created by investorideas is protected by copyright laws other than syndication rights. Investorideas is a news source on Google news and Linkedintoday plus hundreds of syndication partners. Our site does not make recommendations for purchases or sale of stocks or products. Nothing on our sites should be construed as an offer or solicitation to buy or sell products or securities. All investment involves risk and possible loss of investment. This site is currently compensated by featured companies, news submissions, content marketing and online advertising. Contact each company directly for press release questions. Disclosure is posted on each release if required but otherwise the news was not compensated for and is published for the sole interest of our readers. More disclaimer info: http://www.investorideas.com/About/Disclaimer.asp Disclosure: AEMD subscribes to the Investorideas newswire content publishing annual program (9700 per Year, paid quarterly) for news publishing.

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GenSpera (OTCQB:GNSZ) Names JPA Health Communications as Its Agency of Record

GenSpera (OTCQB:GNSZ) Names JPA Health Communications as Its Agency of Record

SAN ANTONIO - January 6, 2015 (Investorideas.com Biotech Newswire) GenSpera, Inc. (OTCQB:GNSZ), a San Antonio based biotech company that develops innovative prodrug therapeutics for the treatment of cancer, announced today that it has named JPA Health Communications as its public relations agency of record.

By leveraging its deep expertise in oncology, JPA will handle GenSpera's external communications for the company and its investigational agent mipsagargin, currently in Phase II clinical development for patients with liver cancer (hepatocellular carcinoma) and brain cancer (glioblastoma).

"This is an exciting time for GenSpera and we are pleased to enlist an agency that understands the complexity of oncology drug development and the important responsibility of engaging the patient community," said Craig Dionne, Ph.D., chief executive officer of GenSpera.

JPA Health Communications is an award-winning communications firm that designs and implements strategic health campaigns for pharmaceutical, non-profit and government clients. As leaders in influencer relations, JPA uses a targeted approach to reach the stakeholders who drive change and deliver measurable results. The agency is headquartered in Washington, D.C., with offices in London and the biotech center of Cambridge, Mass.

"We are honored to be selected to partner with GenSpera at this key time in the company's development," said Carrie Jones, principal and managing director at JPA Health Communications. "GenSpera is an excellent cultural fit with our firm and they share our passion for science and brand communications."

Read this release in full at http://www.investorideas.com/CO/GNSZ/news/2015/01061.asp

About GenSpera

GenSpera's technology platform combines a powerful, plant-derived cytotoxin (thapsigargin) with a prodrug delivery system that provides for the targeted release of drug candidates within a tumor. GenSpera's lead drug candidate, mipsagargin, is activated by the enzyme PSMA, which is found at high levels in the vasculature of liver and glioblastoma cancers, and in the vasculature of almost all other solid tumors. Mipsagargin is therefore expected to have potential efficacy in a wide variety of tumor types. The U.S. Food and Drug Administration (FDA) granted Orphan Drug designation in 2013 for the evaluation of mipsagargin in patients with hepatocellular carcinoma (liver cancer). Mipsagargin Phase II clinical trials are underway in both hepatocellular carcinoma and glioblastoma patients (brain cancer). For more information, please visit the company's website: www.genspera.com or follow us on Twitter @GenSperaNews. Company presentations are available at: http://www.genspera.com/

Cautionary Statement Regarding Forward Looking Information

This news release may contain forward-looking statements. Investors are cautioned that statements in this press release regarding potential applications of GenSpera's technologies constitute forward-looking statements that involve risks and uncertainties, including, without limitation, risks inherent in the development and commercialization of potential products, uncertainty of clinical trial results or regulatory approvals or clearances, need for future capital, dependence upon collaborators and maintenance of our intellectual property rights. Actual results may differ materially from the results anticipated in these forward-looking statements. Additional information on potential factors that could affect our results and other risks and uncertainties will be detailed from time to time in GenSpera's periodic reports filed with the Securities and Exchange Commission.

Disclaimer/Disclosure: The Investorideas.com newswire is a third party publisher of news and research as well as creates original content as a news source. Original content created by investorideas is protected by copyright laws other than syndication rights. Investorideas is a news source on Google news and Linkedintoday plus hundreds of syndication partners. Our site does not make recommendations for purchases or sale of stocks or products. Nothing on our sites should be construed as an offer or solicitation to buy or sell products or securities. All investment involves risk and possible loss of investment. This site is currently compensated by featured companies, news submissions, content marketing and online advertising. Contact each company directly for press release questions. Disclosure is posted on each release if required but otherwise the news was not compensated for and is published for the sole interest of our readers. Disclosure: GNSZ is a previous showcase company which expired on December 18, 2014. Investorideas is long 144 shares

BC Residents and Investor Disclaimer: Effective September 15 2008 - all BC investors should review all OTC and Pink sheet listed companies for adherence in new disclosure filings and filing appropriate documents with Sedar. Read for more info: http://www.bcsc.bc.ca/release.aspx?id=6894. Global investors must adhere to regulations of each country.

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Aethlon Medical (OTCBB: AEMD) Announces Approval of Ebola Treatment Protocol

Medical Technology Breaking News: Aethlon Medical (OTCBB: AEMD) Announces Approval of Ebola Treatment Protocol

SAN DIEGO - January 2, 2015 (Investorideas.com newswire) Aethlon Medical, Inc. (OTCBB:AEMD), the pioneer in developing targeted therapeutic devices to address infectious diseases and cancer, today announced that the United States Food and Drug Administration (FDA) has approved a clinical protocol to treat Ebola-infected individuals in the U.S. with the Aethlon Hemopurifier®. In the treatment of viral pathogens, the Hemopurifier® is a first-in-class bio-filtration device designed for the single-use removal of viruses and shed glycoproteins from the circulatory system of infected individuals. The device targets antiviral drug resistance and serves as a first-line countermeasure against Ebola and other viruses that are not addressed with proven drug therapies.

The approved Ebola treatment protocol allows for an investigational study to be conducted at up to 10 U.S. clinical sites, and up to 20 U.S. subjects may be enrolled to receive the treatment protocol. Patients who meet the enrollment criteria will receive a daily six to eight hour administration of Hemopurifier® therapy until the point that Ebola viral load drops below 1000 copies/ml. The goal of the study is to standardize and evaluate the use of the Hemopurifier® as supportive care in the treatment of Ebola virus disease.

The Ebola treatment protocol resulted from the submission of a supplement to an Investigation Device Exemption (IDE) previously approved by FDA. The supplement was entitled, "Treatment of Ebola Virus Disease (EVD) in Humans with the Aethlon Hemopurifier® Lectin Affinity Plasmapheresis Device." Based on the previously approved IDE protocol, Aethlon is conducting a clinical feasibility study of Hemopurifier® therapy in individuals infected with Hepatitis C virus (HCV) who are also receiving chronic dialysis therapy. A detailed description of the HCV study, including treatment protocol and patient inclusion/exclusion criteria can be accessed online at www.clinicaltrials.gov.

As the approved Ebola treatment protocol is a deviation from the HCV protocol, Aethlon is required to clearly distinguish data collected in the supplemental Ebola protocol study from data derived from the Company's HCV trials. The Company may not combine data from the two studies. Aethlon must also comply with specified patient protection procedures established by the applicable institution including its institutional review board approval prior to treating a patient under the supplement protocol. The Company must also report any unanticipated adverse events resulting from the supplement protocol to the FDA within 10 working days of the use of the device. There is no assurance that any Ebola-infected patients will be treated under the protocol.

Aethlon previously reported that Hemopurifier® therapy was successfully administered to a critically-ill Ebola patient at Frankfurt University Hospital in Germany. On November 14, 2014, the resulting Hemopurifier® treatment data was presented at the American Society of Nephrology (ASN) Annual Meeting by Helmut Geiger, M.D., Chief of Nephrology at Goethe University, Frankfurt University Hospital. Dr. Geiger reported that 242 million Ebola viruses were captured within the Hemopurifier® during treatment, a number verified by a post-treatment elution protocol. The elution protocol has since be repeated, which resulted in second measurement of 253 million copies of Ebola virus captured within the Hemopurifier®.

Dr. Geiger also reported that the patient's viral load prior to the administration of a single 6.5-hour Hemopurifier® treatment was measured at 400,000 virus copies per milliliter of blood (copies/ml). A post-treatment viral load measurement was reported to be 1,000 copies/ml. The treatment was well tolerated with no adverse events reported. At the time of treatment, the Ebola patient was unconscious and suffering from multiple organ failure, which required mechanical ventilation, continuous dialysis and the administration of vasopressor medications. The patient has since made a full recovery and returned home to his family.

Time Magazine recently named the Aethlon Hemopurifier® to be one of the 25 best inventions of 2014. The magazine also included the Hemopurifier® as one of the 11 most remarkable advances in healthcare in 2014.

Read this release in full at http://www.investorideas.com/CO/AEMD/news/2015/01021.asp

About Aethlon Medical, Inc.

Aethlon Medical creates targeted therapeutic devices to address infectious disease, cancer and neurodegenerative disorders. The company's lead product is the Aethlon Hemopurifier®, a first-in-class antiviral and immunotherapeutic device that selectively targets the broad-spectrum elimination of circulating viruses and tumor-secreted exosomes that promote cancer progression. Exosome Sciences, Inc. is a majority owned subsidiary that is advancing exosome-based products to diagnose and monitor cancer, infectious disease and neurological disorders. For more information, please visit http://www.aethlonmedical.com and connect with the Company on Twitter, LinkedIn, Facebook and Google+.

Certain statements herein may be forward-looking and involve risks and uncertainties. Such forward-looking statements involve assumptions, known and unknown risks, uncertainties and other factors which may cause the actual results, performance or achievements of Aethlon Medical, Inc. to be materially different from any future results, performance, or achievements expressed or implied by the forward-looking statements. Such potential risks and uncertainties include, without limitation, that the ESI will not be able to commercialize its future products, that the FDA will not approve the initiation of the Company's clinical programs or provide market clearance of the company's products, future human studies whether revenue or non-revenue generating of the Aethlon ADAPT™ system or the Aethlon Hemopurifier® as an adjunct therapy to improve patient responsiveness to established cancer or hepatitis C therapies or as a standalone cancer or hepatitis C therapy or as a broad spectrum defense against viral pathogens, including ebola, the Company's ability to raise capital when needed, the Company's ability to complete the development of its planned products, the Company's ability to manufacture its products either internally or through outside companies and provide its services, the impact of government regulations, patent protection on the Company's proprietary technology, the ability of the Company to meet the milestones contemplated in the DARPA contract, product liability exposure, uncertainty of market acceptance, competition, technological change, and other risk factors. In such instances, actual results could differ materially as a result of a variety of factors, including the risks associated with the effect of changing economic conditions and other risk factors detailed in the Company's Securities and Exchange Commission filings. The Company undertakes no obligation to publicly update or revise any forward-looking statements, whether as a result of new information, future events, or otherwise.

Contacts:

Leah-Michelle Nebbia (for interview requests) 
Golin 
202-585-2651 
lnebbia@golin.com

James A. Joyce 
Chairman and CEO 
858.459.7800 x301 
jj@aethlonmedical.com

Jim Frakes 
Chief Financial Officer 
858.459.7800 x300 
jfrakes@aethlonmedical.com

Visit this company: www.aethlonmedical.com

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H.C. Wainwright & Co. Initiates Coverage of GenSpera (OTCQB:GNSZ) with a Buy Rating

Biotech Research News: H.C. Wainwright & Co. Initiates Coverage of GenSpera (OTCQB:GNSZ) with a Buy Rating

New York, NY - December 17, 2014 (Investorideas.com Biotech Newswire) Market Exclusive announces that H.C. Wainwright & Co has initiated coverage with a Buy rating of GenSpera, Inc. (OTCQB:GNSZ) and a 12-month target price of $2.

According to the H.C Wainwrights & Co. report, "if successful, Genspera's platform could help provide a novel way to deliver drugs with higher efficiency to specific hard-to-treat cancers, such as HCC and GBM."

GenSpera, Inc., headquartered in San Antonio, Texas, is a biotechnology company specializing in the development of targeted prodrug agents for the treatment of various solid cancers.

About Market Exclusive

Market Exclusive is a financial portal geared to engaging discussion on current financial topics. Market Exclusive is not an investment advisor.

The owner of this announcement warrants that: (i) the releases contained herein are protected by copyright and other applicable laws; and (ii) they are solely responsible for the content, accuracy and originality of the information contained therein.

SOURCE: Market Exclusive

Read this release in full at: http://www.investorideas.com/CO/GNSZ/news/2014/12171.asp

About GenSpera

GenSpera's technology platform combines a powerful, plant-derived cytotoxin (thapsigargin) with a prodrug delivery system that provides for the targeted release of drug candidates within a tumor. Unlike typical chemotherapeutic agents, thapsigargin results in cell death irrespective of the rate of cell division, which may provide an effective approach to kill both fast- and slow-growing cancers. GenSpera's lead drug candidate, mipsagargin, is activated by the enzyme PSMA, which is found at high levels in the vasculature of liver and glioblastoma cancers and in the vasculature of almost all other solid tumors. Mipsagargin is expected to have potential efficacy in a wide variety of tumor types.

The US Food and Drug Administration (FDA) granted Orphan Drug designation in 2013 for the evaluation of mipsagargin in patients with hepatocellular carcinoma. Mipsagargin Phase II clinical trials are underway in both hepatocellular carcinoma (liver cancer) and glioblastoma patients (brain cancer).

For more information, please visit the company's website: www.genspera.com or follow us on Twitter @GenSperaNews.

Company presentations are available at: http://www.genspera.com/

Visit this company: www.genspera.com

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Disclaimer/ Disclosure: Investorideas.com newswire is a third party publisher of news and research as well as creates original content as a news source. Original content created by investorideas is protected by copyright laws other than syndication rights. Investorideas is a news source on Google news and Linkedintoday plus hundreds of syndication partners. Our site does not make recommendations for purchases or sale of stocks or products. Nothing on our sites should be construed as an offer or solicitation to buy or sell products or securities. All investment involves risk and possible loss of investment. This site is currently compensated by featured companies, news submissions, content marketing and online advertising. Contact each company directly for press release questions. Disclosure is posted on each release if required but otherwise the news was not compensated for and is published for the sole interest of our readers. More disclaimer info: http://www.investorideas.com/About/Disclaimer.asp. Disclosure: Genspera (GNSZ) has engaged Investor Ideas for PR and news publication effective June 18, 2014 (compensation of five thousand per month and average of eleven thousand five hundred 144 shares per month)

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