Biotech/Biodefense Stock News; Aethlon Medical (OTCBB: AEMD) Releases Shareholder Letter

SAN DIEGO - April 6, 2011 (Investorideas.com newswire) Aethlon Medical, Inc. (OTCBB: AEMD) disclosed today that its Chairman and CEO, James A. Joyce has issued the following letter to shareholders.

To our Shareholders:
On April 1st, we submitted a contract response to the Defense Advanced Research Projects Agency (DARPA) related to the Dialysis Like Therapeutics (DLT) program referenced in my last shareholder letter. In our submission, we proposed to leverage our technology platform to deliver a dialysis-like therapy that would address precursors to sepsis, including bacterial toxins, viral pathogens, and disease enhancing particles transported by exosomes. We believe our proposal meets goals underlying the DLT program as the resulting device would target to reduce the occurrence of sepsis and would provide decision-free and life saving medical care for the wounded warfighter. Additionally, we introduced an innovative strategy to deliver our dialysis-like therapy without the need for anticoagulants, as well as a novel approach to selectively clear whole bacteria from circulation.
If selected for an award, several larger organizations and industry thought leaders have agreed to partner with us to advance our program proposals. It is anticipated that the DLT program awards will be announced in the next 120 days. We are now collaborating with our advisors to determine the next contract or grant opportunity to pursue. Beyond non-dilutive bioterror and pandemic threat funding opportunities, we are also evaluating potential responses to new government programs in Hepatitis-C, HIV, and Cancer.
In addition to navigating government funding opportunities, we are actively advancing research and clinical initiatives in both infectious disease and cancer. On the clinical front, I am pleased to disclose that we our close to submitting our updated IDE to the FDA. The goal of our submission is approval from the FDA to initiate Hemopurifier� human studies in the United States. Details regarding our FDA communications and clinical site locations can be expected through forthcoming news disclosures.
In regards to our HCV treatment study in India, we initiated treatment of our first patient at the Medanta Medicity Institute, which was observed by our President, Rod Kenley. In previous studies, we demonstrated significant viral load reductions in health compromised dialysis patients that were infected with either HCV or HIV. In this study, we are leveraging those results to demonstrate that our Hemopurifier� can accelerate viral load reduction when administered to non-dialysis patients in combination with drug therapy. Based on a prior clinical validation, we are confident in our capabilities and recognize the potential significance of our Hemopurifier� as viral load depletion rates in the earliest stages of therapy are considered predictive of patients who achieve long-term clinical benefit. In the treatment of our first patient, it was recognized early on that that we needed to modify our protocol to administer anticoagulants in dosages specific to our therapy, and not in amounts normally administered to dialysis patients. Regardless, there was no harm to this patient, although the anticoagulant miscalculation did not allow him to successfully complete his entire treatment. While causing a delay of several weeks, our protocol has been formally amended and we are now ramping up patient enrollment. We are also seeking to open up our study to those residing outside of India, based on worldwide inquiries from infected individuals.
In closing, I also wish to disclose that Jeff Richardson has agreed to rejoin our team on a part-time basis. While you may or may not recall Jeff, he was responsible for originating national news coverage our technology through multiple media outlets, including Popular Science, CNN, and Readers Digest. As the former communications director at Amgen, Jeff provides tremendous insight on advancing the awareness of innovative medical therapies through the national media.
On behalf of our dedicated team at Aethlon Medical, I thank you for your continued support.
Very truly yours,
James A. Joyce
Chairman, CEO
Certain of the statements herein may be forward-looking and involve risks and uncertainties. Such forward-looking statements involve assumptions, known and unknown risks, uncertainties and other factors which may cause the actual results, performance or achievements of Aethlon Medical, Inc. to be materially different from any future results, performance, or achievements expressed or implied by the forward-looking statements. Such potential risks and uncertainties include, without limitation, the capability of the Hemopurifier� to reduce viral loads and other disease conditions or to identify or treat disease conditions such as cancer, including the ability to capture exosomes and the impact that potential ability may have on disease conditions, the Company's ability to raise capital when needed, including obtaining government grants, the Company's ability to complete the development of its planned products, the ability of the Company to obtain FDA and other regulatory approvals permitting the sale of its products, the ability to achieve commercialization in India as a result of the proposed treatment program at Medanta, The Medicity Institute, whether successful or not, the ability of the Hemopurifier� to improve the efficacy of SOC therapy against HCV, the Company's ability to manufacture its products either internally or through outside companies and to create future generations of the Hemopurifier�, the impact of government regulations, patent protection on the Company's proprietary technology, product liability exposure, uncertainty of market acceptance, competition, technological change, and other risk factors. In such instances, actual results could differ materially as a result of a variety of factors, including the risks associated with the effect of changing economic conditions and other risk factors detailed in the Company's Securities and Exchange Commission filings.
Contacts:
James A. Joyce
Chairman, CEO
858.459.7800 x301
jj@aethlonmedical.com
John P. Salvador
Director, Communications & Investor Relations
858.459.7800 x307
jps@aethlonmedical.com

AETHLON MEDICAL INC (OTC BB: AEMD) is a Showcase biotech, biodefense and defense stock on Investorideas.com ($one thousand five hundred per month, $five thousand per month in 144 stock)
Effective March 15, 2011

Biotech/Pharma Stock News; BioSante Pharmaceuticals (NASDAQ: BPAX) to Host LibiGel® R&D Event in New York City

LINCOLNSHIRE, Ill. - April 4, 2011 (Investorideas.com newswire) - BioSante Pharmaceuticals, Inc. (NASDAQ:BPAX) will host a review of female sexual dysfunction (FSD) and the safety of testosterone in women by independent experts, as well as an update of the LibiGel (testosterone gel) development program, for institutional investors and analysts on Thursday, April 7, 2011 in New York City. LibiGel is in Phase III clinical development for the treatment of FSD, specifically, hypoactive sexual desire disorder (HSDD) in menopausal women. Data from both LibiGel Phase III efficacy trials is expected in Fall 2011.

The LibiGel R&D Event will include presentations by independent experts in the fields of FSD and testosterone therapy, and BioSante�s management will speak about the LibiGel Phase III clinical development progress. The independent experts� presentations include:
"Hypoactive Sexual Desire in Postmenopausal Women," by Sheryl Kingsberg, PhD � Chief, Division of Behavioral Medicine, University Hospitals Case Medical Center, MacDonald Women's Hospital; Professor of Reproductive Biology and Psychiatry, Case Western Reserve University School of Medicine, Cleveland, Ohio.
"Update on Testosterone Safety in Women," by Glenn D. Braunstein, MD � Chairman, Department of Medicine, Cedars-Sinai Medical Center, David Geffen School of Medicine at UCLA, Los Angeles, California.
Interested parties may access the presentation slides and an audio recording after the event on BioSante�s website at www.biosantepharma.com.
About LibiGel®
LibiGel is a testosterone gel in Phase III clinical development for the treatment of women who suffer from female sexual dysfunction (FSD). Enrollment has been completed in the two on-going Phase III efficacy trials which are double-blind, placebo-controlled trials of approximately 500 surgically menopausal women each. The efficacy trials are being conducted under an FDA-approved special protocol assessment (SPA) agreement. LibiGel is absorbed quickly through the skin after applying a once-daily pea-sized topical application on the upper arm that delivers testosterone to the bloodstream evenly over time.
In a Phase II trial, LibiGel significantly increased the number of satisfying sexual events in surgically menopausal women suffering from FSD by 238 percent versus baseline (p<0.0001); this increase also was significant versus placebo (p<0.05). In this study, the effective dose of LibiGel produced testosterone blood levels within the normal range for pre-menopausal women and had a safety profile similar to that observed in the placebo group. In addition, no serious adverse events and no discontinuations due to adverse events occurred in any subject receiving LibiGel. The Phase II clinical trial was a double-blind, placebo-controlled trial, conducted in the United States, in surgically menopausal women distressed by their low sexual desire and activity.
BioSante also is conducting a Phase III LibiGel safety study, a randomized, double-blind, placebo-controlled, multi-center, cardiovascular (CV) events and breast cancer study that has enrolled over 3,000 women. The study will continue for a total of five years, however, BioSante can use the safety study data as part of an NDA submission after an average of 12 months of exposure to LibiGel or placebo.
The LibiGel safety study is tracking a predefined list of CV events, in agreement with the FDA, including CV death, myocardial infarction and stroke in women 50 years of age or older and suffering from at least two CV risk factors including hypertension and diabetes. The objective of the safety study is to show the relative safety of testosterone compared to placebo in the number of CV events. The incidence of breast cancer also is being tracked over the course of the study.
About BioSante Pharmaceuticals, Inc.
BioSante is a specialty pharmaceutical company focused on developing products for female sexual health and oncology. BioSante's lead products include LibiGel® (transdermal testosterone gel) for the treatment of female sexual dysfunction (FSD) which is in Phase III clinical development under a U.S. Food and Drug Administration (FDA) Special Protocol Assessment. BioSante also is developing a portfolio of cancer vaccines, four of which have been granted Orphan Drug designation, and are currently in several Phase II clinical trials. Other products in development are Bio-T-Gel™, a testosterone gel for male hypogonadism licensed to Teva Pharmaceuticals and an oral contraceptive in Phase II clinical development using BioSante patented technology. The company also is seeking opportunities for its other technologies. Additional information is available online at: www.biosantepharma.com.
Forward-Looking Statements
To the extent any statements made in this news release deal with information that is not historical, these are forward-looking statements under the Private Securities Litigation Reform Act of 1995. Such statements include, but are not limited to, statements about BioSante's plans, objectives, expectations and intentions with respect to future operations and products, the timing of anticipated regulatory submissions and other statements identified by words such as "will," "potential," "could," "can," "believe," "intends," "continue," "plans," "expects," "anticipates," "estimates," "may," other words of similar meaning or the use of future dates. Forward-looking statements by their nature address matters that are, to different degrees, uncertain. Uncertainties and risks may cause BioSante's actual results to be materially different than those expressed in or implied by BioSante's forward-looking statements. For BioSante, particular uncertainties and risks include, among others, the difficulty of developing pharmaceutical products, obtaining regulatory and other approvals and achieving market acceptance; the marketing success of BioSante's licensees or sublicensees; the success of clinical testing; and BioSante's need for and ability to obtain additional financing. More detailed information on these and additional factors that could affect BioSante's actual results are described in BioSante's filings with the Securities and Exchange Commission, including its most recent annual report on Form 10-K and subsequent quarterly reports on Form 10-Q. All forward-looking statements in this news release speak only as of the date of this news release. BioSante undertakes no obligation to update or revise any forward-looking statement, whether as a result of new information, future events or otherwise.
Contact:
BioSante Pharmaceuticals
For Investors:
The Trout Group LLC
Tricia Swanson
(646) 378-2953
tswanson@troutgroup.com
or
For Media:
McKinney/Chicago
Alan Zachary
(312) 944-6784 ext. 316
azachary@mckinneychicago.com

Disclosure, Disclaimer/ BPAX is a paid advertising client on Investorideas.com (1000 per month).

Emerging Opportunities in Biodefense Part II; An interview with Aethlon Medical (OTCBB: AEMD) CEO, Jim Joyce

Point Roberts, WA - April 1, 2011 � Investorideas.com, a leader in sector research including biotech and biodefense stocks, presents the second in a series of biodefense interviews with Jim Joyce, CEO of Aethlon Medical (OTCBB: AEMD).
Read the first Q&A Interview:
http://www.investorideas.com/CO/AEMD/news/2011/03251.asp
Interview Follow-Up March 31, 2011:
InvestorIdeas: In our interview last week, we discussed the unprecedented opportunity for organizations with treatment candidates against bioterror or pandemic threats to attract non-dilutive funding support from a variety of government agencies. Are these programs really a good use for taxpayer dollars?

Mr. Joyce: Well, with the exception of treatments stockpiled against a few defined threats, our civilian and military populations remain naked against pathogen threats most likely to be weaponized in a bioterror attack or emerge naturally to trigger a pandemic outbreak. However, the fear of the next biological weapon attack or pandemic outbreak is not the only rationale for spending taxpayer dollars on these programs. It should be recognized that these programs provide the impetus for therapeutic innovation that could lead to landmark advances in healthcare.
InvestorIdeas : What kind of therapeutic innovation are we talking about?
Mr. Joyce: Since the focus of government programs has been redirected to supporting broad-spectrum countermeasures, the resulting innovation might be the introduction of life-saving therapies that are effective against pathogens created by man to circumvent traditional drugs and vaccines. Or perhaps, pathogens that might emerge naturally and therefore would not have a corresponding drug or vaccine. Much like the SARS outbreak of 2003. It would seem that such innovation would transcend the treatment of bioterror and pandemic threats to provide new therapeutic strategies against mainstream disease conditions as well.
InvestorIdeas: Do you consider Aethlon Medical to be an innovative company?
Mr. Joyce: Absolutely. Innovation by definition requires taking an entirely different and sometimes more difficult path to achieve an objective. No long ago, it was believed that only drugs or vaccines could address viral infections. We didn't agree. So we created a medical device, the Hemopurifier® that might just redefine the premise of how to treat infectious disease. In fact, we are gathering evidence that suggests our Hemopurifier® has attributes beyond the capabilities of drug agents.
InvestorIdeas: Can you elaborate further on that statement?
Mr. Joyce: First and foremost, I am not aware of any drug candidate that has demonstrated our breadth of capabilities against viral pathogens, and certainly, a vaccine strategy cannot addresses multiple strains, species, and families of viral pathogens. Beyond that, our device fills an unmet medical need of removing immunosuppressive proteins shed by viruses, and we recently discovered our Hemopurifier® captures disease enhancing exosomes that underlie both infectious disease and cancer. Yet, while these attributes may be beyond the reach of traditional drug and vaccine strategies, they offer to improve the benefit of drug and vaccine strategies. In that regard, I would like to think the combination of our device with drugs would provide for a win-win scenario.
InvestorIdeas: In closing, is there anything else you would like to tell us about your Hemopurifier®?
Mr. Joyce: The device has demonstrated great promise in treating HIV and Hepatitis-C patients and it should be considered the leading broad-spectrum treatment countermeasure against biological weapons and naturally emerging pandemic threats. We are now seeking to leverage the technology platform utilized to create our Hemopurifier®, to build new therapeutic candidates to address other disease conditions, including a device targeted to reduce the occurrence of sepsis.
About Aethlon Medical ( OTCBB: AEMD )
At Aethlon Medical, we create revolutionary devices to address infectious disease and cancer. Our devices are designed to be novel platform solutions that fill therapeutic voids or aid in disease diagnosis and monitoring.
Our Hemopurifier® is the first medical device to selectively target the removal of infectious viruses and immunosuppressive proteins from the entire circulatory system. We recently discovered that our Hemopurifier® captures tumor-secreted exosomes that suppress the immune system of those afflicted with cancer. Prior to this discovery, a therapeutic strategy to directly inhibit or reverse the immunosuppressive destruction caused by exosomes did not exist in cancer care. By eliminating this mechanism, we believe our Hemopurifier® can fill an unmet clinical need and provide the benefit of an immune-based therapy without adding drug toxicity or interaction risks to established and emerging treatment strategies.
Human studies have documented the ability of our Hemopurifier® to safely reduce viral load in both Hepatitis-C virus (HCV) and Human Immunodeficiency Virus (HIV) infected patients without the administration of antiviral drugs. However, our initial clinical and commercialization focus is to establish our Hemopurifier® as an adjunct therapy to enhance the benefit of both infectious disease and cancer treatment regimens. In this regard, we plan to commercialize our Hemopurifier® in India as we advance our clinical strategies in the United States and the European Union. In vitro studies conducted by government and non-government research institutes have also verified that our Hemopurifier® has broad-spectrum capabilities against bioterror and emerging pandemic threats. These studies have confirmed the capture of Dengue Hemorrhagic Virus, Ebola Hemorrhagic Virus, Lassa Hemorrhagic Virus, West Nile Virus, H5N1 Avian Influenza Virus, 2009 H1N1 Influenza Virus, the reconstructed Spanish Flu of 1918 Virus, and Monkeypox Virus, which serves as a model for human Smallpox infection.
As a therapeutic device, the Hemopurifier® provides us with a pipeline into four significant market opportunities:
1. Cancer: A treatment candidate to improve patient responsiveness to established cancer therapies by removing immunosuppressive exosomes from circulation.
2. Hepatitis-C Virus (HCV): As an adjunct therapy to accelerate viral load reduction at the outset of standard of care drug regimens.
3. Human Immunodeficiency Virus (HIV): Provides a potential therapeutic option for HIV-infected individuals to manage disease progression once they become resistant to antiviral drug regimens.
4. Bioterror and Pandemic Threats: Represents the most advanced broad-spectrum strategy to address untreatable bioterror and emerging pandemic threats.
The Hemopurifier® is an expansive multi-patented platform technology whose mechanism of action can be leveraged to provide therapeutic, diagnostic, and biomarker discovery solutions. As a therapeutic, the Hemopurifier® is a single-use disposable cartridge designed for implementation within the established infrastructure of dialysis machines and other blood circulatory pumps already located in hospitals and clinics worldwide.
In design, our Hemopurifier® is a selective filtration device containing affinity agents that tightly bind to high-mannose structures unique to the surface of exosomes produced by cancer and glycoproteins residing on the envelope of viruses. These agents are immobilized around approximately 2800 porous hollow fibers that run the interior length of our device. The resulting design provides us the novel ability to separate both exosome and viral targets away from blood cells so they can then be selectively and permanently removed from the circulatory system. In application, blood circulation is established into the Hemopurifier® via a catheter or other blood access device. Once blood flow has been established, treatment benefit is immediate as the entire circulatory system can pass through the Hemopurifier® in as little as 15 minutes.
Our wholly owned subsidiary, Exosome Sciences, Inc. (ESI) is focused on the development of exosome-targeted products and services that improve cancer diagnosis, provide post-treatment cancer surveillance, and aid in the discovery of biomarkers that allow doctors to optimize patient therapy. Additional information regarding Aethlon Medical and Exosome Sciences can be accessed online at www.aethlonmedical.com.
Certain of the statements herein may be forward-looking and involve risks and uncertainties. Such forward-looking statements involve assumptions, known and unknown risks, uncertainties and other factors which may cause the actual results, performance or achievements of Aethlon Medical, Inc. to be materially different from any future results, performance, or achievements expressed or implied by the forward-looking statements. Such potential risks and uncertainties include, without limitation, the company's ability to commercialize its Hemopurifier® in India, capability of the Hemopurifier® to reduce viral loads and other disease conditions or to identify or treat disease conditions such as cancer or Hepatitis-C, including the ability to capture exosomes and the impact that potential ability may have on disease conditions, the Company's ability to raise capital when needed, the Company's ability to complete the development of its planned products, the ability of the Company to obtain FDA and other regulatory approvals permitting the sale of its products, the Company's ability to manufacture its products either internally or through outside companies and provide its services, the impact of government regulations, patent protection on the Company's proprietary technology, product liability exposure, uncertainty of market acceptance, competition, technological change, and other risk factors. In such instances, actual results could differ materially as a result of a variety of factors, including the risks associated with the effect of changing economic conditions and other risk factors detailed in the Company's Securities and Exchange Commission filings.
Contacts:
James A. Joyce
Chairman, CEO
858.459.7800 x301
jj@aethlonmedical.com
About InvestorIdeas.com:
InvestorIdeas.com is a leading global investor and industry research resource portal specialized in sector investing, including biotech stocks with its portal BiotechIndustryStocks.com.
Research more biotech stocks at the Biotech stocks Directory: http://www.investorideas.com/BIS/Stock_List.asp
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AETHLON MEDICAL INC (OTC BB: AEMD) is a Showcase biotech, biodefense and defense stock on Investorideas.com ($one thousand five hundred per month, $five thousand per month in 144 stock)
Effective March 15, 2011

Biotech/Pharma Stock News; BioSante Pharmaceuticals (NASDAQ: BPAX) Completes Enrollment in Both Pivotal LibiGel® Phase III Efficacy Trials

LINCOLNSHIRE, Ill. - March 30, 2011 (Investorideas.com newswire) - BioSante Pharmaceuticals, Inc. (NASDAQ:BPAX) today announced that enrollment of subjects in the second of two pivotal Phase III LibiGel (testosterone gel) safety and efficacy trials has been completed. Enrollment in the first LibiGel efficacy trial was completed in February. The efficacy trials are being conducted under an FDA-approved special protocol assessment (SPA) agreement. LibiGel is in development for the treatment of female sexual dysfunction (FSD), specifically, hypoactive sexual desire disorder (HSDD) in menopausal women, for which there is no FDA-approved product.

"This is an important achievement for BioSante and a key step toward completing the LibiGel Phase III clinical development program," said Joanne Zborowski, BioSante's vice president of clinical development. "There are more than 1,000 subjects in the efficacy trials and we anticipate announcing top-line efficacy data this fall. In addition, we have over 3,000 subjects enrolled in our LibiGel Phase III safety study," she added.
Phillip B. Donenberg, BioSante's senior vice president of finance & CFO commented, "This key LibiGel achievement, coupled with our successful financing strategy, guarantees a solid timeline for Phase III efficacy data, with sufficient funds to finance our operations and LibiGel clinical development through that data and well into 2012. As a result, we have removed near-term financial risk from BioSante without the need for additional funds."
About LibiGel®
LibiGel is a testosterone gel in Phase III clinical development for the treatment of women who suffer from female sexual dysfunction (FSD). Enrollment has been completed in the two on-going Phase III efficacy trials which are double-blind, placebo-controlled trials of approximately 500 surgically menopausal women each. The efficacy trials are being conducted under an FDA-approved special protocol assessment (SPA) agreement. LibiGel is absorbed quickly through the skin after applying a once-daily pea-sized topical application on the upper arm that delivers testosterone to the bloodstream evenly over time.
In a Phase II trial, LibiGel significantly increased the number of satisfying sexual events in surgically menopausal women suffering from FSD by 238 percent versus baseline (p<0.0001); this increase also was significant versus placebo (p<0.05). In this study, the effective dose of LibiGel produced testosterone blood levels within the normal range for pre-menopausal women and had a safety profile similar to that observed in the placebo group. In addition, no serious adverse events and no discontinuations due to adverse events occurred in any subject receiving LibiGel. The Phase II clinical trial was a double-blind, placebo-controlled trial, conducted in the United States, in surgically menopausal women distressed by their low sexual desire and activity.
BioSante also is conducting a Phase III LibiGel safety study, a randomized, double-blind, placebo-controlled, multi-center, cardiovascular (CV) events and breast cancer study that has enrolled over 3,000 women. The study will continue for a total of five years, however, BioSante can use the safety study data as part of an NDA submission after an average of 12 months of exposure to LibiGel or placebo.
The LibiGel safety study is tracking a predefined list of CV events, in agreement with the FDA, including CV death, myocardial infarction and stroke in women 50 years of age or older and suffering from at least two CV risk factors including hypertension and diabetes. The objective of the safety study is to show the relative safety of testosterone compared to placebo in the number of CV events. The incidence of breast cancer also is being tracked over the course of the study.
About BioSante Pharmaceuticals, Inc.
BioSante is a specialty pharmaceutical company focused on developing products for female sexual health and oncology. BioSante's lead products include LibiGel® (transdermal testosterone gel) for the treatment of female sexual dysfunction (FSD) which is in Phase III clinical development under a U.S. Food and Drug Administration (FDA) Special Protocol Assessment. BioSante also is developing a portfolio of cancer vaccines, four of which have been granted Orphan Drug designation, and are currently in several Phase II clinical trials. Other products in development are Bio-T-Gel™, a testosterone gel for male hypogonadism licensed to Teva Pharmaceuticals and an oral contraceptive in Phase II clinical development using BioSante patented technology. The company also is seeking opportunities for its other technologies. Additional information is available online at: www.biosantepharma.com.
Forward-Looking Statements
To the extent any statements made in this news release deal with information that is not historical, these are forward-looking statements under the Private Securities Litigation Reform Act of 1995. Such statements include, but are not limited to, statements about BioSante's plans, objectives, expectations and intentions with respect to future operations and products, the timing of anticipated regulatory submissions and other statements identified by words such as "will," "potential," "could," "can," "believe," "intends," "continue," "plans," "expects," "anticipates," "estimates," "may," other words of similar meaning or the use of future dates. Forward-looking statements by their nature address matters that are, to different degrees, uncertain. Uncertainties and risks may cause BioSante's actual results to be materially different than those expressed in or implied by BioSante's forward-looking statements. For BioSante, particular uncertainties and risks include, among others, the difficulty of developing pharmaceutical products, obtaining regulatory and other approvals and achieving market acceptance; the marketing success of BioSante's licensees or sublicensees; the success of clinical testing; and BioSante's need for and ability to obtain additional financing. More detailed information on these and additional factors that could affect BioSante's actual results are described in BioSante's filings with the Securities and Exchange Commission, including its most recent annual report on Form 10-K and subsequent quarterly reports on Form 10-Q. All forward-looking statements in this news release speak only as of the date of this news release. BioSante undertakes no obligation to update or revise any forward-looking statement, whether as a result of new information, future events or otherwise.
Contact:
BioSante Pharmaceuticals
For Investors:
The Trout Group LLC
Tricia Swanson
(646) 378-2953
tswanson@troutgroup.com
or
For Media:
McKinney/Chicago
Alan Zachary
(312) 944-6784 ext. 316
azachary@mckinneychicago.com

Disclosure, Disclaimer/ BPAX is a paid advertising client on Investorideas.com (1000 per month).

Biotech/Pharma Snapshot; Advances in Cancer Immunotherapy; (OTCBB: AEMD), (NYSE: BMY), Dendreon Corporation (NasdaqGS: DNDN)

Point Roberts, WA - March 29, 2011- Investorideas.com , an investor research portal specializing in sector research including biotech and pharma stocks, reports on advances in Cancer Immunotherapy. Bristol-Myers Squibb Company (NYSE:BMY) announced Friday that the U.S. Food and Drug Administration (FDA) approved YERVOY� (ipilimumab) 3 mg/kg for the treatment of patients with unresectable (inoperable) or metastatic melanoma.

Bristol-Myers Squibb Company (NYSE:BMY) hit a 52 week high on Friday.
"The approval of YERVOY illustrates the power of harnessing the patient's own immune system to combat cancer," stated Jim Joyce, CEO of Aethlon Medical. "With the recent approval of PROVENGE from Dendreon, the cancer immunotherapy era seems to be well underway. In this regard, we believe that the elimination of particles released by cancers to suppress the immune response would further unlock the benefit of Yervoy, Provenge, and other immunotherapy candidates in the clinical pipeline."
Aethlon Medical (OTCBB: AEMD) recently discovered that it's Hemopurifier®, a dialysis-like device with broad-spectrum capabilities to capture infectious viral pathogens from circulation, also captures tumor-secreted exosomes that cause programmed cell death of the immune cells required to fight cancer.
Dendreon Corporation (NasdaqGS: DNDN ) was the first to receive FDA approval for its
PROVENGE® (sipuleucel-T) immune cell treatment of cancer. According to the company, it is the first autologous cellular immunotherapy AUTOLOGOUS CELLULAR IMMUNOTHERAPYPROVENGE is classified by the FDA as an autologous cellular immunotherapy. It is designed to be an active cellular immunotherapy. Closeto receive FDA approval for the treatment of asymptomatic or minimally symptomatic metastatic castrate resistant prostate cancer. PROVENGE is designed to induce an immune response against prostate cancer.
RecentBristol-Myers Squibb Company (NYSE:BMY) News:
FDA Approves YERVOY™ (ipilimumab) for the Treatment of Patients with Newly Diagnosed or Previously-Treated Unresectable or Metastatic Melanoma, the Deadliest Form of Skin Cancer
First and Only Approved Therapy for Unresectable or Metastatic Melanoma to Demonstrate a Significant Improvement in Overall Survival
First FDA-Approved Therapy for Unresectable or Metastatic Melanoma in More than a Decade
First Approved Cancer Immunotherapy for Melanoma to Target CTLA-4 and First FDA-Approved Compound in the Company's Robust Immuno-Oncology Pipeline Risk Evaluation and Mitigation Strategy Developed with FDA to Support the Safe and Appropriate Use of YERVOY and Help Inform Patients and Providers About Important Safety Risks
PRINCETON, N.J. - (Investorideas.com Newswire) - Bristol-Myers Squibb Company (NYSE:BMY) announced that the U.S. Food and Drug Administration (FDA) approved YERVOY™ (ipilimumab) 3 mg/kg for the treatment of patients with unresectable (inoperable) or metastatic melanoma. YERVOY is the first and only therapy for unresectable or metastatic melanoma to demonstrate a significant improvement in overall survival based on results from a pivotal randomized, double-blind Phase 3 study. Median overall survival was 10 months (95% CI: 8.0-13.8) for YERVOY, 6 months (95% CI: 5.5-8.7) for gp100 and 10 months (95% CI: 8.5-11.5) for YERVOY + gp100, with p-values of 0.0026 (not adjusted for multiple comparisons) for YERVOY and 0.0004 for YERVOY + gp100 vs. gp100, respectively. As published in the New England Journal of Medicine, the Kaplan-Meier estimated survival rate at 1 year was 46% (95% CI: 37.0, 54.1) in the YERVOY arm vs. 25% (95% CI: 18.1, 32.9) in the gp100 arm. The estimated survival rate at 2 years was 24% (95% CI: 16.0, 31.5) in the YERVOY arm vs. 14%2 (95% CI: 8.0, 20.0) in the gp100 arm. YERVOY, which is a recombinant, human monoclonal antibody, is the first FDA-approved cancer immunotherapy that blocks the cytotoxic T- lymphocyte antigen-4 (CTLA-4).
Full News: http://www.investorideas.com/news/2011/main/03281.asp
Biotech/Pharma Sector Snapshot Trading March 28th
Aethlon Medical (OTCBB: AEMD) traded in a range: $0.13 - 0.1380
Bristol-Myers Squibb Company (NYSE: BMY ) Day's Range: $26.94 - $27.38 on over 18 Million shares
Dendreon Corporation (NasdaqGS: DNDN ) closed at $33.96, up $1.01 (3.07%) with further gains in after hours trading.
Company Snapshot
About Aethlon Medical (OTCBB: AEMD)
At Aethlon Medical, we create revolutionary devices to address infectious disease and cancer. Our devices are designed to be novel platform solutions that fill therapeutic voids or aid in disease diagnosis and monitoring.
Our Hemopurifier® is the first medical device to selectively target the removal of infectious viruses and immunosuppressive proteins from the entire circulatory system. We recently discovered that our Hemopurifier® captures tumor-secreted exosomes that suppress the immune system of those afflicted with cancer. Prior to this discovery, a therapeutic strategy to directly inhibit or reverse the immunosuppressive destruction caused by exosomes did not exist in cancer care. By eliminating this mechanism, we believe our Hemopurifier® can fill an unmet clinical need and provide the benefit of an immune-based therapy without adding drug toxicity or interaction risks to established and emerging treatment strategies.
Human studies have documented the ability of our Hemopurifier® to safely reduce viral load in both Hepatitis-C virus (HCV) and Human Immunodeficiency Virus (HIV) infected patients without the administration of antiviral drugs. However, our initial clinical and commercialization focus is to establish our Hemopurifier® as an adjunct therapy to enhance the benefit of both infectious disease and cancer treatment regimens. In this regard, we plan to commercialize our Hemopurifier® in India as we advance our clinical strategies in the United States and the European Union. In vitro studies conducted by government and non-government research institutes have also verified that our Hemopurifier® has broad-spectrum capabilities against bioterror and emerging pandemic threats. These studies have confirmed the capture of Dengue Hemorrhagic Virus, Ebola Hemorrhagic Virus, Lassa Hemorrhagic Virus, West Nile Virus, H5N1 Avian Influenza Virus, 2009 H1N1 Influenza Virus, the reconstructed Spanish Flu of 1918 Virus, and Monkeypox Virus, which serves as a model for human Smallpox infection.
As a therapeutic device, the Hemopurifier® provides us with a pipeline into four significant market opportunities:
1.Cancer: A treatment candidate to improve patient responsiveness to established cancer therapies by removing immunosuppressive exosomes from circulation.
2.Hepatitis-C Virus (HCV): As an adjunct therapy to accelerate viral load reduction at the outset of standard of care drug regimens.
3.Human Immunodeficiency Virus (HIV): Provides a potential therapeutic option for HIV-infected individuals to manage disease progression once they become resistant to antiviral drug regimens.
4.Bioterror and Pandemic Threats: Represents the most advanced broad-spectrum strategy to address untreatable bioterror and emerging pandemic threats.
The Hemopurifier® is an expansive multi-patented platform technology whose mechanism of action can be leveraged to provide therapeutic, diagnostic, and biomarker discovery solutions. As a therapeutic, the Hemopurifier® is a single-use disposable cartridge designed for implementation within the established infrastructure of dialysis machines and other blood circulatory pumps already located in hospitals and clinics worldwide.
In design, our Hemopurifier® is a selective filtration device containing affinity agents that tightly bind to high-mannose structures unique to the surface of exosomes produced by cancer and glycoproteins residing on the envelope of viruses. These agents are immobilized around approximately 2800 porous hollow fibers that run the interior length of our device. The resulting design provides us the novel ability to separate both exosome and viral targets away from blood cells so they can then be selectively and permanently removed from the circulatory system. In application, blood circulation is established into the Hemopurifier® via a catheter or other blood access device. Once blood flow has been established, treatment benefit is immediate as the entire circulatory system can pass through the Hemopurifier® in as little as 15 minutes.
Our wholly owned subsidiary, Exosome Sciences, Inc. (ESI) is focused on the development of exosome-targeted products and services that improve cancer diagnosis, provide post-treatment cancer surveillance, and aid in the discovery of biomarkers that allow doctors to optimize patient therapy. Additional information regarding Aethlon Medical and Exosome Sciences can be accessed online at www.aethlonmedical.com.
Certain of the statements herein may be forward-looking and involve risks and uncertainties. Such forward-looking statements involve assumptions, known and unknown risks, uncertainties and other factors which may cause the actual results, performance or achievements of Aethlon Medical, Inc. to be materially different from any future results, performance, or achievements expressed or implied by the forward-looking statements. Such potential risks and uncertainties include, without limitation, the company's ability to commercialize its Hemopurifier® in India, capability of the Hemopurifier® to reduce viral loads and other disease conditions or to identify or treat disease conditions such as cancer or Hepatitis-C, including the ability to capture exosomes and the impact that potential ability may have on disease conditions, the Company's ability to raise capital when needed, the Company's ability to complete the development of its planned products, the ability of the Company to obtain FDA and other regulatory approvals permitting the sale of its products, the Company's ability to manufacture its products either internally or through outside companies and provide its services, the impact of government regulations, patent protection on the Company's proprietary technology, product liability exposure, uncertainty of market acceptance, competition, technological change, and other risk factors. In such instances, actual results could differ materially as a result of a variety of factors, including the risks associated with the effect of changing economic conditions and other risk factors detailed in the Company's Securities and Exchange Commission filings .
Contacts:
James A. Joyce
Chairman, CEO
858.459.7800 x301
jj@aethlonmedical.com
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Effective March 15, 2011

Q&A with Stephen M. Simes, President and CEO of BioSante Pharmaceuticals (NASDAQ: BPAX); Update on LibiGel®, Pipeline and Recent Research Report

How a Specialty Pharmaceutical Company Leads the Way; Phase III Clinicals for the Only
Product Currently Addressing Female Sexual Dysfunction

March 28 , 2011 - (Investorideas.com newswire.com) Investorideas.com, an investor research
portal covering leading sectors including biotech stocks and pharma stocks, features an exclusive
Q&A interview and update with Mr. Stephen M. Simes, President and Chief Executive Officer of
BioSante Pharmaceuticals.

Stephen M. Simes, discusses how specializing in a product for female sexual dysfunction and
leading in development with LibiGel® in Phase III clinicals, makes BioSante Pharmaceuticals
(NASDAQ: BPAX) a company to watch.

JMP Securities released a report this month with a price target of $5.00. Mr. Simes gives his
insight as the company’s leader as to why the future looks so bright.

BioSante Pharmaceuticals Interview

Q: Investorideas.com
As you move forward with development of LibiGel® and other products in the pipeline, is your
company able to execute in terms of funding and cash available ? – and up to what time period?

A: Stephen M. Simes, President and Chief Executive Officer of BioSante Pharmaceuticals
It is quite interesting that a full 13 years after Viagra was approved for treating men’s
sexual issues, women still do not have an approved product to treat their sexual health.
Today, BioSante is the only company in the world in Phase III clinical development for the
treatment of women’s sexual dysfunction, specifically hypoactive sexual desire disorder.
This represents a major opportunity for BioSante and women since we expect to be first to
market with our LibiGel which is in several Phase III studies.

Q: Investorideas.com
JMP Securities recently released research on your company as an “underfollowed and
undervalued microcap company” and has placed a $5.00 target price. They note “Our $5
price target is derived by applying a 5x multiple to our base case projection for LibiGel sales
of $422MM in 2016, discounted by 30% per year. “ Can you comment on their revenue
projections ?

A: Stephen M. Simes, President and Chief Executive Officer of BioSante Pharmaceuticals
We believe the market potential for products like LibiGel is over $1 billion. This is derived
from many factors including the fact that the erectile dysfunction market in the U.S. alone
is over $2 billion and the market for male testosterone products is over $1 billion.

Q: Investorideas.com
The Company recently reported financial results and a pipeline update . Can you give us a

summary of what the pipeline looks like outside of LibiGel® ?

A: Stephen M. Simes, President and Chief Executive Officer of BioSante Pharmaceuticals
Yes, we have a full pipeline of products. Elestrin is our already approved estrogen product for the
treatment of hot flashes in menopausal women and Bio-T-Gel is our male testosterone product.
We hope to announce an FDA submission of Bio-T-Gel in the near future. In addition, we have a
full portfolio of cancer vaccines in clinical trials.

About LibiGel® LibiGel® is a gel formulation of testosterone in development that is quickly
absorbed through the skin after a once-daily application of a pea-sized dose of gel on the upper
arm, delivering testosterone to the bloodstream evenly over time and in a non-invasive and
painless manner. Though generally characterized as a male hormone, testosterone also is
present in women and its deficiency has been found to decrease libido or sex drive. In addition,
studies have shown that testosterone therapy can increase bone density, raise energy levels and
improve mood, in addition to boosting sexual desire and activity.

Currently, BioSante is conducting three Phase III clinical studies to demonstrate the safety
and efficacy of LibiGel to increase sexual desire and satisfying sexual events and to decrease
distress associated with the decreased desire. Two Phase III safety and efficacy trials that are
underway are randomized, double-blind, placebo-controlled trials which will enroll approximately
500 surgically menopausal women each for six-months of treatment. BioSante is conducting
these trials under an FDA agreed special protocol assessment (SPA). In addition, BioSante has
another SPA agreement with the FDA related to treatment of naturally menopausal women.
The SPA process and agreement confirms the FDA’s position that FSD and HSDD are true
conditions that women experience, with measurable endpoints, that can be evaluated and which
deserve therapeutic options. It also affirms that the FDA agrees that the LibiGel Phase III safety
and efficacy clinical trial design, clinical endpoints, sample size, planned conduct and statistical
analyses are acceptable to support regulatory approval. Further, it provides assurance that these
agreed measures will serve as the basis for regulatory review and the decision by the FDA to
approve an NDA for LibiGel.

About BioSante Pharmaceuticals, Inc. (NASDAQ: BPAX)
BioSante (NASDAQ: BPAX) is a specialty pharmaceutical company focused on developing
products for female sexual health and oncology. BioSante’s lead products include LibiGel®
(transdermal testosterone gel) for the treatment of female sexual dysfunction (FSD) which is
in Phase III clinical development under a U.S. Food and Drug Administration (FDA) Special
Protocol Assessment. BioSante’s first FDA-approved product is Elestrin™ (estradiol gel)
indicated for the treatment of hot flashes associated with menopause, marketed in the U.S.
by Azur Pharma, BioSante’s licensee. BioSante also is developing a portfolio of cancer
vaccines, four of which have been granted Orphan Drug designation, and are currently in
several Phase II clinical trials. Other products are Bio-T-Gel™, a testosterone gel for male
hypogonadism licensed to Teva Pharmaceuticals and an oral contraceptive in Phase II clinical
development using BioSante patented technology. Additional information is available online at:
www.biosantepharma.com.

Visit the company profile on Investorideas.com: http://www.investorideas.com/CO/BPAX/
Or the company website www.biosantepharma.com to learn more about BioSante.

Request News & Updates from BioSante (NASDAQ: BPAX) on the Investorideas.com sign up
page: http://www.investorideas.com/Resources/Newsletter.asp

Recent Research

JMP Securities

We are initiating coverage on BioSante Pharmaceuticals with a Market Outperform rating
and price target of $5. We view BioSante as an underfollowed and undervalued microcap
company with a late-stage development asset that has better than average clinical risk.
BioSante's lead product candidate is LibiGel, a proprietary formulation of testosterone delivered
through the skin being developed for the treatment of female sexual dysfunction, for which there
is currently no approved therapy. We believe that with clarity emerging on timelines for key value-
driving LibiGel catalysts, institutional interest will increase and the market inefficiency in the
current valuation can begin to resolve. Our $5 price target is derived by applying a 5x multiple to
our base case projection for LibiGel sales of $422MM in 2016, discounted by 30% per year.
Full report :
http://www.investorideas.com/CO/BPAX/news/Initiating-Coverage-031611.pdf

About InvestorIdeas.com:

InvestorIdeas.com is a leading global investor and industry research resource portal specialized
in sector investing covering over thirty industry sectors and global markets including China,
India, the Middle East and Australia. Our leading biotech portal within our content umbrella,
www.BiotechIndustryStocks.com, covers the biotech/pharma sector for independent investors
with company profiles, news and stock directories.

Disclaimer: The following BioSante Pharmaceuticals, Inc company profile is a paid for submission (one thousand per
month) Our sites do not make recommendations. Nothing on our sites should be construed as an offer or solicitation
to buy or sell products or securities. We attempt to research thoroughly, but we offer no guarantees as to the accuracy
of information presented. All Information relating to featured companies is sourced from public documents and/ or the
company and is not the opinion of our web sites. This site is currently compensated by featured companies, news
submissions, company profile submissions and online advertising. http://www.investorideas.com/About/Disclaimer.asp
Disclosure: http://www.investorideas.com/About/News/Clientspecifics.asp

Forward-Looking Statements

To the extent any statements made in this news release deal with information that is not historical, these are forward-
looking statements under the Private Securities Litigation Reform Act of 1995. Such statements include, but are
not limited to, statements about BioSante's plans, objectives, expectations and intentions with respect to future
operations and products, the timing of anticipated regulatory submissions and other statements identified by words such
as "will," "potential," "could," "can," "believe," "intends," "continue," "plans," "expects," "anticipates," "estimates," "may,"
other words of similar meaning or the use of future dates. Forward-looking statements by their nature address matters that
are, to different degrees, uncertain. Uncertainties and risks may cause BioSante's actual results to be materially different
than those expressed in or implied by BioSante's forward-looking statements. For BioSante, particular uncertainties
and risks include, among others, the difficulty of developing pharmaceutical products, obtaining regulatory and other
approvals and achieving market acceptance; the marketing success of BioSante's licensees or sublicensees; the success
of clinical testing; and BioSante's need for and ability to obtain additional financing. More detailed information on these
and additional factors that could affect BioSante's actual results are described in BioSante's filings with the Securities
and Exchange Commission, including its most recent annual report on Form 10-K and subsequent quarterly reports on
Form 10-Q. All forward-looking statements in this news release speak only as of the date of this news release. BioSante
undertakes no obligation to update or revise any forward-looking statement, whether as a result of new information, future
events or otherwise.

For info about BioSante Pharmaceuticals, Inc

Contact:
For Investors:

The Trout Group LLC
Tricia Swanson
(646) 378-2953; tswanson@troutgroup.com

For Additional Information about Investorideas.com:

C Van Zant: 800-665-0411 – cvanzant@investorideas.com

Source – Investorideas.com

Emerging Opportunities in Biodefense; An interview with Aethlon Medical (OTCBB: AEMD) CEO, Jim Joyce

Point Roberts, WA. March 25, 2011 – Investorideas.com, a leader in sector research including

biotech and biodefense stocks, presents an interview with Jim Joyce, CEO of Aethlon Medical

(OTCBB: AEMD).

InvestorIdeas: What opportunities exist for small organizations that want to participate in

the emerging biodefense industry?

Jim Joyce, CEO of Aethlon Medical (OTCBB: AEMD)

Multiple opportunities have recently surfaced for small organizations with innovative

countermeasures against bioterror threats, and more are expected in the near future. As an

example, Freemind Group, an industry advisory organization reported this week that they are

witnessing a dramatic and unprecedented surge in biodefense and infectious disease funding

opportunities from various government institutes. They anticipate that funding applications

submitted during the coming months of May, June, and July alone will result in cumulative awards

of approximately $500,000,000.00. In fact, some of these awards are not capped and can exceed

$50,000,000 for clinical trial support. For small organizations, such non-dilutive awards offer to

transform business capabilities and reward patient shareholders.

InvestorIdeas: That’s certainly exciting, but how can small organizations like Aethlon

Medical compete against big pharma for such awards?

Jim Joyce, CEO of Aethlon Medical

In reality, both big pharma and large biotechnology players have demonstrated little interest

in responding to these programs. As a result, government agencies are primarily reliant on

innovation stemming from research advanced by small organizations, which from a historical

basis, is likely to be the principal source of innovation anyway. Still, these programs do not

exist to solely support research. Recently created agencies like the Biomedical Research and

Development Authority (known as BARDA) provide support for post R&D activities including

clinical studies, manufacturing, and other activities that may be required to transition a candidate

treatment countermeasure into the strategic national stockpile.

InvestorIdeas: Do you feel Aethlon Medical is positioned to benefit from these programs?

Mr. Joyce: I feel we are extremely well positioned to benefit as government policies to protect

against bioterror and pandemic threats have been redefined to focus support towards broad-

spectrum countermeasures that are able to address multiple pathogen threats. Based on pre-

clinical and clinical data, we believe our Hemopurifier® is the most advanced and perhaps only

true broad-spectrum countermeasure. While traditional therapeutics often struggle to address

multiple strains of the same pathogen, third party researchers have demonstrated that our

Hemopurifier® captures different species of many of the most deadly viral threats known to man.

These include Dengue, Ebola, and Lassa Hemorrhagic Viruses, West Nile Virus, H5N1 Avian

Influenza Virus, the 2009 H1N1 Influenza Virus, the reconstructed Spanish Flu of 1918, and

Monkeypox Virus, which is the primary model for testing treatments against human Smallpox

infection.

InvestorIdeas: Have you conducted any human studies with your Hemopurifier®

Jim Joyce, CEO of Aethlon Medical

Yes, we have advanced our technology into human studies, which demonstrated safety and the

observation of significant viral load reductions in both hepatitis-C and HIV infected individuals

without the administration of antiviral drug therapies. We are now advancing a clinical program

whose objective is to utilize our Hemopurifier® as an adjunct strategy to improve the benefit

of hepatitis-C standard-of-care drug therapy without adding drug toxicity and interaction risks.

We are quite excited about this clinical program, as therapeutic filtration of hepatitis-C from

plasma has previously proven to have a remarkable effect in improving treatment outcomes

when combined with drug therapy.

opportunity, I feel confident that we are advancing a leading broad-spectrum therapeutic strategy

to address viral threats, and that our strategy fulfills strategic objectives recently mandated by

our government.

treatment countermeasures that may also have mainstream commercial market applications in

disease conditions such as hepatitis-C, HIV, and cancer.

InvestorIdeas: Is Aethlon Medical currently pursuing any contract or grant opportunities?

Jim Joyce, CEO of Aethlon Medical
Yes. In the coming days we will submit a formal response to a military program opportunity
entitled “Dialysis Like Therapeutics”. The stated goal of this program is the creation of a medical
device that would save the lives of thousands of military patients each year. While our response
is challenging, it has also been rewarding as we have attracted several groups to partner and
participate in our submission. Once our response is in, we will then convene with our advisors to
determine the next contract opportunity to focus our efforts towards.

InvestorIdeas: In closing, is there any advice you would provide to other organizations

that might be interested in participating in the biodefense and pandemic threat industry?

Jim Joyce, CEO of Aethlon Medical

By nature, the opportunity to address the looming threat of biological weapons and naturally

Regardless, as it specifically relates to our biodefense

We also benefit from a policy shift that no longer precludes the support of

emerging pandemic threats will be enduring and the industry is still very young. However, my

advise for small organizations is to be sure they have therapeutic strategies in place to address

established disease conditions with real commercial markets before venturing into a field where

targeted disease conditions may or may not emerge and the primary source of support is

government funding.

About Aethlon Medical (OTCBB: AEMD)

At Aethlon Medical, we create revolutionary devices to address infectious disease and cancer.
Our devices are designed to be novel platform solutions that fill therapeutic voids or aid in
disease diagnosis and monitoring.

Our Hemopurifier® is the first medical device to selectively target the removal of infectious
viruses and immunosuppressive proteins from the entire circulatory system. We recently
discovered that our Hemopurifier® captures tumor-secreted exosomes that suppress the immune
system of those afflicted with cancer. Prior to this discovery, a therapeutic strategy to directly
inhibit or reverse the immunosuppressive destruction caused by exosomes did not exist in cancer
care. By eliminating this mechanism, we believe our Hemopurifier® can fill an unmet clinical need
and provide the benefit of an immune-based therapy without adding drug toxicity or interaction
risks to established and emerging treatment strategies.

Human studies have documented the ability of our Hemopurifier® to safely reduce viral load
in both Hepatitis-C virus (HCV) and Human Immunodeficiency Virus (HIV) infected patients
without the administration of antiviral drugs. However, our initial clinical and commercialization
focus is to establish our Hemopurifier® as an adjunct therapy to enhance the benefit of both
infectious disease and cancer treatment regimens. In this regard, we plan to commercialize
our Hemopurifier® in India as we advance our clinical strategies in the United States and the
European Union. In vitro studies conducted by government and non-government research
institutes have also verified that our Hemopurifier® has broad-spectrum capabilities against
bioterror and emerging pandemic threats. These studies have confirmed the capture of Dengue
Hemorrhagic Virus, Ebola Hemorrhagic Virus, Lassa Hemorrhagic Virus, West Nile Virus, H5N1
Avian Influenza Virus, 2009 H1N1 Influenza Virus, the reconstructed Spanish Flu of 1918 Virus,
and Monkeypox Virus, which serves as a model for human Smallpox infection.

As a therapeutic device, the Hemopurifier® provides us with a pipeline into four significant market
opportunities:
1. Cancer: A treatment candidate to improve patient responsiveness to established cancer
therapies by removing immunosuppressive exosomes from circulation.
2. Hepatitis-C Virus (HCV): As an adjunct therapy to accelerate viral load reduction at the outset
of standard of care drug regimens.
3. Human Immunodeficiency Virus (HIV): Provides a potential therapeutic option for HIV-infected
individuals to manage disease progression once they become resistant to antiviral drug regimens.
4. Bioterror and Pandemic Threats: Represents the most advanced broad-spectrum strategy to
address untreatable bioterror and emerging pandemic threats.

The Hemopurifier® is an expansive multi-patented platform technology whose mechanism
of action can be leveraged to provide therapeutic, diagnostic, and biomarker discovery
solutions. As a therapeutic, the Hemopurifier® is a single-use disposable cartridge designed
for implementation within the established infrastructure of dialysis machines and other blood
circulatory pumps already located in hospitals and clinics worldwide.

In design, our Hemopurifier® is a selective filtration device containing affinity agents that
tightly bind to high-mannose structures unique to the surface of exosomes produced by cancer

and glycoproteins residing on the envelope of viruses. These agents are immobilized around
approximately 2800 porous hollow fibers that run the interior length of our device. The resulting
design provides us the novel ability to separate both exosome and viral targets away from blood
cells so they can then be selectively and permanently removed from the circulatory system. In
application, blood circulation is established into the Hemopurifier® via a catheter or other blood
access device. Once blood flow has been established, treatment benefit is immediate as the
entire circulatory system can pass through the Hemopurifier® in as little as 15 minutes.

Our wholly owned subsidiary, Exosome Sciences, Inc. (ESI) is focused on the development of
exosome-targeted products and services that improve cancer diagnosis, provide post-treatment
cancer surveillance, and aid in the discovery of biomarkers that allow doctors to optimize patient
therapy. Additional information regarding Aethlon Medical and Exosome Sciences can be
accessed online at www.aethlonmedical.com.

Certain of the statements herein may be forward-looking and involve risks and uncertainties.
Such forward-looking statements involve assumptions, known and unknown risks, uncertainties
and other factors which may cause the actual results, performance or achievements of Aethlon
Medical, Inc. to be materially different from any future results, performance, or achievements
expressed or implied by the forward-looking statements. Such potential risks and uncertainties
include, without limitation, the company's ability to commercialize its Hemopurifier® in India,
capability of the Hemopurifier® to reduce viral loads and other disease conditions or to identify or
treat disease conditions such as cancer or Hepatitis-C, including the ability to capture exosomes
and the impact that potential ability may have on disease conditions, the Company's ability to
raise capital when needed, the Company's ability to complete the development of its planned
products, the ability of the Company to obtain FDA and other regulatory approvals permitting
the sale of its products, the Company's ability to manufacture its products either internally or
through outside companies and provide its services, the impact of government regulations, patent
protection on the Company's proprietary technology, product liability exposure, uncertainty of
market acceptance, competition, technological change, and other risk factors. In such instances,
actual results could differ materially as a result of a variety of factors, including the risks
associated with the effect of changing economic conditions and other risk factors detailed in the
Company's Securities and Exchange Commission filings.

Contacts:
James A. Joyce
Chairman, CEO
858.459.7800 x301
jj@aethlonmedical.com

About InvestorIdeas.com:
InvestorIdeas.com is a leading global investor and industry research resource portal specialized
in sector investing, including biotech stocks with its portal BiotechIndustryStocks.com.

Research more biotech stocks at the Biotech stocks Directory: http://www.investorideas.com/BIS/
Stock_List.asp

Visit the showcase page on Investorideas.com
http://www.investorideas.com/CO/AEMD

Get added to the company’s news alerts:
http://www.investorideas.com/Resources/Newsletter.asp

Disclaimer/ Disclosure : The Investorideas.com is a third party publisher of news and research
Our sites do not make recommendations, but offer information portals to research news,
articles, stock lists and recent research. Nothing on our sites should be construed as an offer or

solicitation to buy or sell products or securities. This site is currently compensated by featured
companies, news submissions and online advertising. AETHLON MEDICAL INC (OTC BB:
AEMD) Showcase biotech, biodefense and defense stock on Investorideas.com ($one thousand
five hundred per month, $five thousand per month in 144 stock) Effective March 15, 2011

800-665-0411 – dvanzant@investorideas.com
Source - Investorideas.com