Vancouver, British Columbia - June 20, 2012 (Investorideas.com Newswire) Sirona Biochem Corp. ( TSX-V: SBM , OTC: SRBCF, Frankfurt: ZSB), announced today results from a preclinical study of its sodium glucose transporter (SGLT) inhibitor in monkeys. When administered orally, Sirona Biochem’s SGLT inhibitor, SBM-TFC-039, triggered glucosuria in a dose-dependent manner. In addition, the glucosuria effect was robust for the full 24 hours studied.
data that may differentiate SBM-TFC-039 from the other SGLT inhibitors in development," he added.
SBM-TFC-039 is an SGLT inhibitor drug candidate for Type 2
diabetes. In the kidneys, SGLT inhibitors reduce the reabsorption of
glucose into the bloodstream by eliminating excess glucose into the
SBM-TFC-039 has been tested acutely and chronically in a rodent
diabetic model, in addition to the latest study in primates. In those
tests, SBM-TFC-039 has consistently demonstrated a glucose-lowering
effect in a dose-dependent manner.
About Sirona Biochem Corp.
Sirona Biochem is a biotechnology company developing diabetes
therapeutics, cancer vaccine antigens, skin depigmenting and anti-aging
agents for cosmetic use, and biological ingredients. The company
utilizes a proprietary chemistry technique to improve pharmaceutical
properties of carbohydrate-based molecules. For more information visit
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required by law.
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