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Tuesday, December 13, 2011

Biotech Stock Investor News Alert; Aethlon Medical (OTCBB: AEMD) Announces HIV-AIDS Research Discovery

San Diego, December 13, 2011 - (Investorideas.com Newswire) Aethlon Medical, Inc. (OTCBB:AEMD), the pioneer in developing therapeutic filtration devices to address infectious disease and cancer, announced today that researchers have discovered that the Aethlon Hemopurifier® is able to capture particles known as Nef protein exosomes, which contribute to the progression of human immunodeficiency virus (HIV) infection to acquired immunodeficiency syndrome (AIDS). The Aethlon Hemopurifier® is a first-in-class therapeutic device that selectively targets the clearance of viruses, immunosuppressive proteins, and disease enhancing exosomes from the entire the entire circulatory system.
Nef or "Negative Factor" protein is a highly abundant HIV accessory protein that plays an essential role in AIDS progression, yet has eluded HIV drug discovery efforts. Nef protein is secreted from infected cells in small membrane-bound packages called "exosomes." These exosomes fuse with non-infected cells and cause a variety of effects, including programmed cell death of CD4+ immune cells, the hallmark of AIDS. The Hemopurifier ® provides a strategy to address Nef exosomes, which are present in the blood of HIV infected individuals. In an ex vivo validation study conducted by researchers at Morehouse School of Medicine, a small-scale Hemopurifier® reduced the presence of Nef exosomes in cell-culture fluids by greater than 85% in less than 24 hours. The outcome represents the first demonstration that a medical device can selectively target Nef exosomes.
"It is becoming increasingly clear that many viruses, including HIV, exploit the mechanisms of exosome production for their secretion and pathogenesis," stated Michael Powell, Ph.D., Associate Professor and Director of Proteomics, Microbiology, Biochemistry, and Immunology at Morehouse School of Medicine. "Therefore, therapies that target circulating exosomes hold great promise to advance antiviral strategies."
In addition to Nef exosomes, the Hemopurifier® is the subject of multi-cancer studies against tumor-secreted exosomes that facilitate the ability of cancerous tumors to evade the immune response. Tumor-secreted exosomes are implicated in the survival, growth, and metastasis of cancer. Additionally, the Hemopurifier® is being evaluated in human studies as an adjunct therapy to improve outcomes of HCV patients receiving interferon therapy.
" First and foremost, our clinical focus is to demonstrate that our Hemopurifier® improves the benefit of Hepatitis-C virus (HCV) therapies, stated Jim Joyce, CEO and founder of Aethlon Medical. "However, when considering our previous HIV treatment experience, the emerging insight that we can address Nef exosomes provides a further basis for us to pursue clinical opportunities to treat HIV-infected individuals," stated Jim Joyce, CEO and founder of Aethlon Medical.
In a previous proof-of-principle study, an HIV-infected dialysis patient diagnosed with AIDS received Hemopurifier® therapy during his normal dialysis treatment, resulting in the administration of three weekly Hemopurifier® treatments over the period of one month. The study was conducted in the absence of any antiviral drug administration. In addition to demonstrating treatment safety in an immune-compromised AIDS patient, HIV viral load of the patient was reduced from 102,759 iu/ml at the beginning of treatment one to a final value of 7,978 iu/ml at the end of treatment twelve, representing a 92% reduction. Viral load remained 56% below initial testing values when measured 14-days after last Hemopurifier(r) therapy. Additionally, CD4 t-cell to lymphocyte ratios increased from 13.5% to 18.05% during the study. A ratio below 15% represents a clinical definition of AIDS. The study was conducted at the Sigma New Life Hospital in India.
About Aethlon Medical (OTCBB: AEMD)
The Aethlon Medical mission is to create innovative medical devices that address unmet medical needs in cancer, infectious disease, and other life-threatening conditions. Our Aethlon ADAPT™ System is a revenue-stage technology platform that provides the basis for a new class of therapeutics that target the selective removal of disease enabling particles from the entire circulatory system. The Aethlon ADAPT™ product pipeline includes the Aethlon Hemopurifier® to address infectious disease and cancer; HER2osome™ to target HER2+ breast cancer, and a medical device being developed under a contract with the Defense Advanced Research Projects Agency (DARPA) that would reduce the incidence of sepsis in combat-injured soldiers and civilians. For more information, please visit www.aethlonmedical.com.
Certain of the statements herein may be forward-looking and involve risks and uncertainties. Such forward-looking statements involve assumptions, known and unknown risks, uncertainties and other factors which may cause the actual results, performance or achievements of Aethlon Medical, Inc. to be materially different from any future results, performance, or achievements expressed or implied by the forward-looking statements. Such potential risks and uncertainties include, without limitation, the ability for the Company to derive business partnerships or future revenue streams using the Aethlon ADAPT™ system including the ability to introduce a targeted breast cancer therapy known as HER2osome™, there is no assurance that FDA will approve the initiation of the company's clinical programs or provide market clearance of the company's products, the ability to achieve the goals set out in the DARPA contract, future human studies of the Aethlon Hemopurifier® as an adjunct therapy to improve patient responsiveness to established cancer therapies, the Hemopurifier's® ability to capture tumor-secreted exosomes and to captureNef protein exosomes and the impact that capture may have on disease conditions, the ability to successfully complete the Medanta HCV study and achieve positive results, the company's ability to raise capital when needed, the Company's ability to complete the development of its planned products, the Company's ability to manufacture its products either internally or through outside companies and provide its services, the impact of government regulations, patent protection on the Company's proprietary technology, product liability exposure, uncertainty of market acceptance, competition, technological change, and other risk factors. In such instances, actual results could differ materially as a result of a variety of factors, including the risks associated with the effect of changing economic conditions and other risk factors detailed in the Company's Securities and Exchange Commission filings.
Contact:
James A. Joyce
Chairman and CEO
858.459.7800 x301
jj@aethlonmedical.com
Jody Cain
Senior Vice President, Lippert/Heilshorn & Associates
310.691.7100
jcain@lhai.com
Jim Frakes
Chief Financial Officer
858.459.7800 x300
jfrakes@aethlonmedical.com
John P. Salvador
Director, Communications
858.459.7800 x307
jps@aethlonmedical.com
Learn more about OTCBB: AEMD
http://www.investorideas.com/CO/AEMD/
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6 comments:

  1. Good day My Name is bele aide from south african, i am here to share a great testimony of my life. i was cure from HIV by a Doctor Name, DR okemuen i have been HIV for 5 year. i saw doctor Email on the internet so i contact him and i explain to him i follow up the instruction behold 6 days later after taking the cure i went for a HIV text to my surprise it was Negative my family doctor was surprise my husband who abandon me was surprise my brother if you no that you are positive please i will advise you to contact him now and see for your self his Email is drokemuenhealingtemple@gmail.com
    and also you can contact him +2348158178729

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  2. ALL THANKS TO DR.SUKU FOR CURING ME FROM HIV/AIDS I AM SO HAPPY TO GIVE THIS TESTIMONY ANY TYPE OF SICKNESS HERE SOLUTION DR SUKU.

    Thank Dr Suku herbalist therapies that could totally treat this virus from the body meanwhile i saw so many proofs and lots of testimonies to that effect. A friend referred me to Dr.Suku from Africa who cured him from HIV/AIDS and told me that he could cure me from HIV. At first i never believed until i did made contact with him and told me not to worry that he will help me out, I received the cure from him through DHL DELIVER. But to my surprise it work and my doctor confirmed it too who could believe that a herbal medicine can cure HIV so if you have any problem HIV, HERPES, CANCER, ALS,HEPATITIS B, DIABETIC,My advice to you all who thinks that their is no cure for herpes that is Not true just contact him and get cure from Dr Suku healing spell cure of all kinds of sickness you may have.Remember delay in treatment leads to death email him greatsukusolutiontemple@hotmail.com or call +2348074839242.via website; http://greatsukusolutiont.wix.com/dr-suku

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  3. ALL THANKS TO DR.SUKU FOR CURING ME FROM HIV/AIDS I AM SO HAPPY TO GIVE THIS TESTIMONY ANY TYPE OF SICKNESS HERE SOLUTION DR SUKU.

    Thank Dr Suku herbalist therapies that could totally treat this virus from the body meanwhile i saw so many proofs and lots of testimonies to that effect. A friend referred me to Dr.Suku from Africa who cured him from HIV/AIDS and told me that he could cure me from HIV. At first i never believed until i did made contact with him and told me not to worry that he will help me out, I received the cure from him through DHL DELIVER. But to my surprise it work and my doctor confirmed it too who could believe that a herbal medicine can cure HIV so if you have any problem HIV, HERPES, CANCER, ALS,HEPATITIS B, DIABETIC,My advice to you all who thinks that their is no cure for herpes that is Not true just contact him and get cure from Dr Suku healing spell cure of all kinds of sickness you may have.Remember delay in treatment leads to death email him greatsukusolutiontemple@hotmail.com or call +2348074839242.via website; http://greatsukusolutiont.wix.com/dr-suku..

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  4. AGAIN THIS IS UNBELIEVABLE BUT IT DID HAPPEN..
    Few Months ago i went for check up in the hospital, the doctor took my blood for test and told me to come after 3 days for the results, after 3 days passed i went back to the hospital for the results,and it was then the doctor told me that i was diagnosed with HIV and he told me to come back after 6 months for my medication.
    On that very day i was left with no happiness and everything in life became meaningless to me, i began to think on how i could get rid of this virus from my body, i decided to go on internet and do some research, while i was surfing the internet i came across some good testimonials on how Dr Molemen has been using his herbal medicine to treat and save different patients from various diseases and infections, i also saw someone who was commenting on how she was cured from HIV with the medicine.
    To me i never believed in them, that was the first time to come across something like that, i just decided to try it out if it did really worked!
    They gave the contact details of Dr Molemen and i copied his email and later that night i sent him a message concerning my health.
    He later gave me a response and then we talked about the medicine and he said to me he was going to send the medicine to my home address and that he needed my address of where i reside.
    I sent him all he requested for in other to get the medicine ready for me, and after 3 days i received a mail from the Post Office and to my surprised it was the herbal medicine from Dr Molemen.
    He explained to me on how i was to take the medicine, he said i was to take 2 times daily for 14 days, i followed exactly as i was told, before he sent me the medicine he said that i should go for check up after finish drinking the medicine, so after i finished the medicine i went back to the hospital for check up and told my greatest surprise again i was told that i am negative, i know someone would not believed this, but it did happened to a brother like me, i have always dreamed of living in good health again, thank god everything went well for me and thank god for Dr Molemen Miracle Healing Medicine, you can reach Dr Molemen at ( drmolemenspiritualtemple@gmail.com or ( dr.molemenspiritualtemple@yahoo.com) or call him on +2347036013351, friends this man has a cure to all human disease, do not believe in medical drugs, let try some Natural Remedy.
    Forever remain grateful Doc....

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  5. Greatest Joy in my life today HIV/AIDS has cure but doctor said HIV Disease has no cure until i met Dr.SABU who help me in my life. I was infected with HIV/AIDS DISEASE in 2012, i went to many hospitals for cure but there was no solution, so I was thinking how can I get a solution,so that my body can be okay.until this faithful day as i was browsing the net I saw a testimony on how Dr.SABU helped people in curing HIV disease, quickly I copied his Email which is drsabuspelltemple@gmail.com so i contacted him for solution for my HIV DISEASE,so Dr.SABU told me that his going to prepare herbal medicine for my health,then he prepared the medicine and luckily after 2week my HIV we be cured.Dr.SABU is well recognize as one of the best herbalist doctor in Africa, you don't have to be sad anymore or share your tears anymore on this disease when the cure have already be found by Dr.SABU herbal medicine,he so cure HPV,CANCER,HERPES,ALS,HEPATITIS B, DIABETIC, ASTHMA,contact him via website;https://drsabuspelltemple.wixsite.com/dr-sabu or whatsapp number:+2347057624993.

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  6. HOW I GOT RID OF MY 2YEARS GENITAL HERPES WITHIN 7 DAYS,GOD IS AWEASOME! THIS IS REAL,PLEASE DON'T IGNORE.Call/Text me via; +2347033330164 I caught genital herpes from my Ex Husband in 2015,he never told me about the virus. I had it for 2 years with so many outbreak,and it affected my life.. People think herpes is really a minor skin irritation herpes has a long term effects on health. The stigma attached to this virus by ignorant people is ridiculous. Most people have herpes in one form or another,i was first taking Antiviral medicines, such as acyclovir(Zovirax), famciclovir (Famvir), and valacyclovir (Valtrex), are recommended for treating primary genital herpes outbreaks. This medicine can be taken when an outbreak occurs. It can also be taken every day to help prevent outbreaks,it is not a total cure... I will like to tell everyone who is reading this my testimony on how i get rid of my genital herpes.I was reading a comment on the internet,and i saw a testimony posted by a young lady from USA that she got rid of her herpes with the help of doctor IDAHOSA,a Traditional Herbalist.So i was so happy when i saw that post,that his herbal medication Cure the virus totally.I quickly copied the herbal doctor email address and i email him within 30 minutes he respond to my mail.I explain things to him he told me not to worry that i should fill his herbal form which i did..The next day he told me that he has prepare the herbal medicine,that i should send him my address that he want to sent his HERBAL MEDICINE to me via DHL or FED-EX that was how i got the herbal medication and i use it as i was instructed.After a week i went to see a Medical Doctor who confirmed my herpes was no more.When some of my friend who has herpes saw me they were surprise and i also introduce them to the man and they are also cure from the same Genital herpes today.I also refer my cousin to the same herbalist who was having HIV and today she is fully cure...If you have Genital or Oral herpes or any kind of Diseases and infections,kindly contact DR. IDAHOSA via this email;hsvnaturalremedyclinic@gmail.com He also have a herbal cure for many other DISEASES and INFECTIONS,this is not scam is 100% Real.

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