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Thursday, December 2, 2010

Investor Video; BioSante (NASDAQ: BPAX) CEO Discusses BioSante Portfolio of Cancer Vaccines

CEO reports, “There are fifteen BioSante cancer vaccine Phase I and Phase II studies
ongoing in different cancers.”

Point Roberts, WA, LINCOLNSHIRE, Ill –December 2, 2010 (Investorideas.com Newswire)
Investorideas.com, an investor research portal specialized in sector investing including biotech
and pharma stocks, releases a video presentation featuring BioSante Pharmaceuticals, Inc.
(NASDAQ: BPAX) for interested investors.

The video, featuring Stephen M. Simes, President and CEO, was recorded during “Cancer
Immunotherapy: A Long Awaited Reality”, a conference hosted by BioBusiness.TV and MD
Becker Partners on October 21st, 2010, at the New York Academy of Medicine. Mr. Simes
discusses the GVAX wide portfolio of cancer vaccines.

Mr. Simes reports, “There are fifteen BioSante cancer vaccine Phase I and Phase II studies
ongoing in different cancers.”

Watch BioSante’s segment on Cancer Vaccines for the Cancer Immunotherapy
Conference the following link is provided: http://www.biobusiness.tv/report-on-location/
biosante-presentation-at-cancer-immunotherapy-conference-1548/

Highlights from the Cancer Vaccines Product Page:

Read the Full info at: http://www.biosantepharma.com/Cancer-Vaccines.php

BioSante Pharmaceuticals Inc. is developing a pipeline of Immunotherapies (cancer vaccines).
BioSante’s cancer vaccines use cell lines that are genetically modified to secrete granulocyte-
macrophage colony-stimulating factor (GM-CSF), an immunostimulant. The cells then are
irradiated to prevent further cell division; however the cells remain metabolically active.

Currently, BioSante’s Cancer Vaccines are in various Phase I and Phase II cancer clinical
trials and may represent the widest portfolio (cancer types) of cancer vaccines in development.
Studies are conducted primarily at Johns Hopkins Cancer Center and are sponsored/funded
by The Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, various philanthropies,
foundations and the National Cancer Institute

Cancer Types Being Studied:

•Leukemia
◦Chronic Myeloid Leukemia (CML)
◦Acute Myeloid Leukemia (AML)
•Pancreatic Cancer
•Breast Cancer
•Multiple Myeloma
•Melanoma
•Colorectal
Prostate Cancer

Chronic Myeloid Leukemia (CML) — Results of a Phase II clinical trial
Of 19 patients treated with GVAX CML, 7 had complete remission.

•Gleevec was taken for at least one year (range 13-53 months) pre-vaccine and then GVAX CML

was administered while the patients remained on a stable dose of Gleevec.
◦19 patients enrolled (median of 72 months of follow-up)
◦13 patients (8 of whom had increasing disease burden before vaccination): the number of
remaining cancer cells declined
◦12 patients reached their lowest levels of residual cancer cells to date following vaccination
◦7 patients had complete remission
"We want to get rid of every last cancer cell in the body, and using cancer vaccines may be a
good way to mop up residual disease," said lead investigator Hyam Levitsky, M.D., professor
of oncology, medicine and urology at the Johns Hopkins Kimmel Cancer Center in Baltimore,
Maryland.

Acute Myeloid Leukemia (AML) — Results of Phase II
Patients treated with GVAX had both a relapse-free survival and overall survival rate
improvement of approximately 30% compared with the non-GVAX-treated subjects.

•GVAX AML was accompanied by immunotherapy-primed lymphocytes after autologous stem cell
transplantation.
◦54 subjects enrolled
◦28 (52%) received a pre-transplantation GVAX AML dose
◦46 (85%) subjects achieved complete remission during the treatment period. Of these patients,
the 3-year relapse-free survival (RFS) rate was:
■47.4% in non-GVAX treated patients
■61.8% in the GVAX-treated group
■Overall survival (OS) rate in all subjects was 57.4%
■Overall survival (OS) rate was 73.4% in the GVAX-treated group
■In summary, patients treated with GVAX had both a relapse-free survival and overall survival
rate improvement of approximately 30% compared with the non-GVAX-treated subjects

Read more on BioSante’s Cancer Vaccines and clinical trial info at: http://
www.biosantepharma.com/Cancer-Vaccines.php

Research more biotech stocks at the Biotech stocks Directory: http://
www.investorideas.com/BIS/Stock_List.asp

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If you have any questions regarding information in this press release please contact the company
listed in the press release.
Contact BioSante Pharmaceuticals

For Investors:
The Trout Group LLC
Tricia Swanson
(646) 378-2953
tswanson@troutgroup.com
or
For Media:

McKinney/Chicago
Alan Zachary
(312) 944-6784 ext. 316
azachary@mckinneychicago.com

The content from the investor Fact sheet and opinions from http://
www.biosantepharma.com/downloads/BioSante-Fact-Sheet.pdf are not the opinion of
Investorideas.com or related websites.

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